Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DBH | P09172 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 14/20 | 0.39 |
| ▸ | RXRB | P28702 | 8/20 | 0.38 |
| ▸ | RARB | P10826 | 7/20 | 0.38 |
| ▸ | RARG | P13631 | 6/20 | 0.38 |
| ▸ | RXRG | P48443 | 4/20 | 0.38 |
| ▸ | RARA | P10276 | 5/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1446400 | 0.94 | KDM4E (0.41) | KDM4EDBHGAARECQLRXRA | |
| SCHEMBL15241273 | 0.91 | RXRA (0.39) | KDM4EDBHGAARECQLRXRA | |
| SCHEMBL21617582 | 0.83 | KDM4E (0.35) | KDM4EDBHGAARECQLRXRA | |
| SCHEMBL14345091 | 0.82 | KDM4E (0.35) | KDM4EDBHGAARECQLRXRA | |
| SCHEMBL17285600 | 0.81 | RXRA (0.42) | KDM4ERECQLRXRARXRBRARB | |
| SCHEMBL29565418 | 0.81 | RXRA (0.55) | KDM4ERECQLRXRARXRBRARB | |
| SCHEMBL9817816 | 0.81 | RXRA (0.55) | KDM4ERECQLRXRARXRBRARB | |
| SCHEMBL527839 | 0.81 | RXRA (0.55) | KDM4ERECQLRXRARXRBRARB | |
| SCHEMBL21617328 | 0.81 | KDM4E (0.33) | KDM4EDBHGAARECQLRXRA | |
| SCHEMBL14627417 | 0.79 | RXRA (0.40) | KDM4ERECQLRXRARXRBRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987159-A | HIGH EFFICIENCY | FRATELLI LAMBERTI S.P.A. (IT) | 1991-01-22 | — | — | US | claimed |
| EP-3154925-B1 | PROCESS FOR THE PREPARATION OF A PHENYLINDAN COMPOUND | IGM RESINS ITALIA SRL (IT) | 2018-08-01 | — | — | EP | disclosed |
| EP-3154925-B1 | PROCESS FOR THE PREPARATION OF A PHENYLINDAN COMPOUND | IGM RESINS ITALIA SRL (IT) | 2018-08-01 | — | — | EP | disclosed |
| US-10017435-B2 | Process for the preparation of a phenylindan compound | IGH RESINS ITALIA S.R.L. | 2018-07-10 | — | — | US | disclosed |
| US-10017435-B2 | Process for the preparation of a phenylindan compound | IGH RESINS ITALIA S.R.L. | 2018-07-10 | — | — | US | disclosed |
| US-10017435-B2 | Process for the preparation of a phenylindan compound | IGH RESINS ITALIA S.R.L. | 2018-07-10 | — | — | US | disclosed |
| US-20180141882-A1 | PROCESS FOR THE PREPARATION OF A PHENYLINDAN COMPOUND | IGM RESINS ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |
| US-20180141882-A1 | PROCESS FOR THE PREPARATION OF A PHENYLINDAN COMPOUND | IGM RESINS ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |
| US-20180141882-A1 | PROCESS FOR THE PREPARATION OF A PHENYLINDAN COMPOUND | IGM RESINS ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |
| EP-3154925-A1 | PROCESS FOR THE PREPARATION OF A PHENYLINDAN COMPOUND | IGM Resins Italia S.r.l. (IT) | 2017-04-19 | — | — | EP | disclosed |
| EP-1620382-B1 | PROCESS FOR THE PREPARATION OF 1-PHENYLINDAN PHOTOINITIATORS | BASF SE (DE) | 2013-09-04 | — | — | EP | disclosed |
| EP-1620382-B1 | PROCESS FOR THE PREPARATION OF 1-PHENYLINDAN PHOTOINITIATORS | BASF SE (DE) | 2013-09-04 | — | — | EP | disclosed |
| US-20110065962-A1 | PROCESS FOR THE PREPARATION OF AROMATIC ALPHA-HYDROXY KETONES | MENEGUZZO ENZO | 2011-03-17 | — | — | US | disclosed |
| US-7307192-B2 | Process for the preparation of 1-phenylindan photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-12-11 | — | — | US | disclosed |
| US-7307192-B2 | Process for the preparation of 1-phenylindan photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-12-11 | — | — | US | disclosed |
| US-7307192-B2 | Process for the preparation of 1-phenylindan photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-12-11 | — | — | US | disclosed |
| US-20060241323-A1 | Process for the preparation of 1-phenylindan photoinitiators | IGM GROUP B.V. (NL) | 2006-10-26 | — | — | US | disclosed |
| EP-1620382-A1 | PROCESS FOR THE PREPARATION OF 1-PHENYLINDAN PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099111-A1 | PROCESS FOR THE PREPARATION OF 1-PHENYLINDAN PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-11-18 | — | — | WO | disclosed |
| US-4987159-A | HIGH EFFICIENCY | FRATELLI LAMBERTI S.P.A. (IT) | 1991-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065962-A1 | PROCESS FOR THE PREPARATION OF AROMATIC ALPHA-HYDROXY KETONES | KHK, BCKDK, PAH | KDM4E 1014/4885DBH 23/4885GAA 1031/4885 |
| US-10017435-B2 | Process for the preparation of a phenylindan compound | CYP1A1, HPD, CYP1B1 | KDM4E 956/4885DBH 983/4885GAA 4340/4885 |
| US-20180141882-A1 | PROCESS FOR THE PREPARATION OF A PHENYLINDAN COMPOUND | CYP1A1, HPD, CYP1B1 | KDM4E 956/4885DBH 983/4885GAA 4340/4885 |
| US-20060241323-A1 | Process for the preparation of 1-phenylindan photoinitiators | CYP1B1, INF2, TFPI | KDM4E 1853/4885DBH 2499/4885GAA 743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.