SCHEMBL2143395

SCHEMBL2143395

CCCCC[SiH2]O[SiH2]CCCCC

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
THRB P10828 1/20 0.41
SLC22A1 O15245 3/20 0.40
SLC22A2 O15244 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.36
ALDH1A1 P00352 2/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36
LMNA P02545 1/20 0.35
DNM1 Q05193 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5012163 0.97 TSHR (0.47) TSHRTHRBSLC22A1SLC22A2SMN1; SMN2
SCHEMBL18600561 0.94 TSHR (0.44) TSHRTHRBSLC22A1SLC22A2SMN1; SMN2
SCHEMBL9840435 0.90 TSHR (0.38) TSHRTHRBSLC22A1SLC22A2SMN1; SMN2
SCHEMBL4411318 0.89 TSHR (0.40) TSHRTHRBSLC22A1SLC22A2SMN1; SMN2
SCHEMBL7546695 0.84 TSHR (0.40) TSHRTHRBSLC22A1ALDH1A1HSD17B10
SCHEMBL15260490 0.80 TSHR (0.30) TSHRTHRB
SCHEMBL11467631 0.80 TSHR (0.36) TSHRTHRB
SCHEMBL6545836 0.79 TSHR (0.47) TSHRTHRBSLC22A1ALDH1A1HSD17B10
SCHEMBL7657115 0.79
SCHEMBL1000117 0.78 TSHR (0.35) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996012723-A1 PROCESS FOR PREPARING ALKYLSILYL OR ARYLSILYL ETHERS FMC CORPORATION (US) 1996-05-02 WO claimed
US-5493044-A Process for preparing alkylsilyl or arylsilyl ethers FMC CORPORATION (US) 1996-02-20 US claimed
EP-4604951-A1 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF AMIRA THERAPEUTICS, S.L. (ES) 2025-08-27 EP disclosed
WO-2024083861-A1 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF SELABTEC SCIENCES, SLU (ES) 2024-04-25 WO disclosed
WO-2024074604-A1 COMPOUNDS FOR THE MANAGEMENT OF CELL STEMNESS AND INVASION IN CANCER AND RELATED DISEASES INSTITUTO BIOMAR, S.A (ES) 2024-04-11 WO disclosed
CN-112839995-A Epoxy resin composition 巴斯夫欧洲公司 2021-05-25 CN disclosed
EP-3703666-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS Universidade de Santiago de Compostela (ES) 2020-09-09 EP disclosed
US-9896547-B2 Polymerization method and polymers formed therewith THE SCRIPPS RESEARCH INSTITUTE (US) 2018-02-20 US disclosed
EP-2925803-B1 POLYMERIZATION METHOD AND POLYMERS FORMED THEREWITH SCRIPPS RESEARCH INST (US) 2017-11-29 EP disclosed
US-20170218127-A1 POLYMERIZATION METHOD AND POLYMERS FORMED THEREWITH THE SCRIPPS RESEARCH INSTITUTE. 2017-08-03 US disclosed
US-9624344-B2 Polymerization method and polymers formed therewith THE SCRIPPS RESEARCH INSTITUTE (US) 2017-04-18 US disclosed
WO-2006038172-A1 NEW PIPERIDINE ANTIBIOTICS ACTELION PHARMACEUTICALS LTD (CH) 2006-04-13 WO disclosed
EP-1412346-A1 METHOD FOR PRODUCING NOVEL SPINOSYN DERIVATIVES Bayer CropScience AG (DE) 2004-04-28 EP disclosed
WO-2003010155-A1 METHOD FOR PRODUCING NOVEL SPINOSYN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2003-02-06 WO disclosed
WO-1996012723-A1 PROCESS FOR PREPARING ALKYLSILYL OR ARYLSILYL ETHERS FMC CORPORATION (US) 1996-05-02 WO disclosed
WO-1996012723-A1 PROCESS FOR PREPARING ALKYLSILYL OR ARYLSILYL ETHERS FMC CORPORATION (US) 1996-05-02 WO disclosed
US-5493044-A Process for preparing alkylsilyl or arylsilyl ethers FMC CORPORATION (US) 1996-02-20 US disclosed
US-5493044-A Process for preparing alkylsilyl or arylsilyl ethers FMC CORPORATION (US) 1996-02-20 US disclosed
US-5493044-A Process for preparing alkylsilyl or arylsilyl ethers FMC CORPORATION (US) 1996-02-20 US disclosed
US-5202444-A 1L-1,2:5,6-di-O-cyclohexylidene-chiro-inositol derivatives; intermediates for diols and hydroxycarboxylic acids and esters and antibiotics THE YOKOHAMA RUBBER CO., LTD. (JP) 1993-04-13 US disclosed