Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28966482 | 1.00 | TSHR (0.47) | TSHRTHRBSLC22A1ALDH1A1HSD17B10 | |
| SCHEMBL18600561 | 0.97 | TSHR (0.44) | TSHRTHRBSLC22A1ALDH1A1HSD17B10 | |
| SCHEMBL2143395 | 0.97 | TSHR (0.41) | TSHRTHRBSLC22A1ALDH1A1HSD17B10 | |
| SCHEMBL4411318 | 0.92 | TSHR (0.40) | TSHRTHRBSLC22A1ALDH1A1HSD17B10 | |
| SCHEMBL9840435 | 0.88 | TSHR (0.38) | TSHRTHRBSLC22A1ALDH1A1HSD17B10 | |
| SCHEMBL7546695 | 0.87 | TSHR (0.40) | TSHRTHRBSLC22A1ALDH1A1HSD17B10 | |
| SCHEMBL11467631 | 0.83 | TSHR (0.36) | TSHRTHRB | |
| SCHEMBL6545836 | 0.82 | TSHR (0.47) | TSHRTHRBSLC22A1ALDH1A1HSD17B10 | |
| SCHEMBL1000117 | 0.81 | TSHR (0.35) | TSHRTHRB | |
| SCHEMBL9463372 | 0.81 | TSHR (0.35) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896480-A1 | CRIPOWELLINS AND SYNTHETIC DERIVATIVES THEREOF USED AS MEDICAMENTS | Bayer CropScience Aktiengesellschaft (DE) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006136309-A1 | CRIPOWELLINS AND SYNTHETIC DERIVATIVES THEREOF USED AS MEDICAMENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | WO | disclosed |
| EP-1412346-A1 | METHOD FOR PRODUCING NOVEL SPINOSYN DERIVATIVES | Bayer CropScience AG (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003010155-A1 | METHOD FOR PRODUCING NOVEL SPINOSYN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2003-02-06 | — | — | WO | disclosed |
| US-6238931-B1 | PARTICLES WITH ENERGY DONORS AND ACCEPTORS AS WELL AS PROTEINS, POLYPEPTIDES, NUCLEIC ACIDS, OR LIGAND ANALOGUES BOUND TO SURFACE; WITH REDUCED QUENCHING AND IMPROVED FLUORESCENCE INTENSITIES; IMMUNOASSAYS | BIOSITE DIAGNOSTICS, INC. | 2001-05-29 | — | — | US | disclosed |