SCHEMBL7546695

SCHEMBL7546695

CCCCCC[SiH2]O[SiH2]C

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
THRB P10828 1/20 0.40
DNM1 Q05193 7/20 0.32
ALDH1A1 P00352 3/20 0.32
LMNA P02545 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HSD17B10 Q99714 1/20 0.32
SLC22A1 O15245 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9700048 0.89 TSHR (0.35) TSHRTHRB
SCHEMBL28966482 0.87 TSHR (0.47) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL5012163 0.87 TSHR (0.47) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL18600561 0.84 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL2143395 0.84 TSHR (0.41) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL4411318 0.80 TSHR (0.40) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL11467631 0.76 TSHR (0.36) TSHRTHRB
SCHEMBL6545836 0.76 TSHR (0.47) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9840435 0.75 TSHR (0.38) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL9463372 0.75 TSHR (0.35) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020017940-A1 COMPOSITION FOR MANUFACTURING ELECTROMAGNETIC WAVE SHIELDING GASKET, AND ELECTROMAGNETIC WAVE SHIELDING GASKET 주식회사 이에스디웍 2020-01-23 WO disclosed
US-6475622-B2 FILM OF UNIFORM THICKNESS TOYO SEIKAN KAISHA LTD. (JP) 2002-11-05 US disclosed
US-20020058115-A1 Process for forming silicon oxide coating on plastic material NAMIKI TSUNEHISA (JP) 2002-05-16 US disclosed
US-6254983-B1 SUITABLE FOR PACKAGING AND OTHER PURPOSES. TOYO SEIKAN KAISHA LTD. (JP) 2001-07-03 US disclosed
EP-0719877-A1 Process for forming silicon oxide coatings TOYO SEIKAN KAISHA, LTD. (JP) 1996-07-03 EP disclosed