Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2143395 | 0.90 | TSHR (0.41) | TSHRLMNATHRBSLC22A1SLC22A2 | |
| SCHEMBL5012163 | 0.88 | TSHR (0.47) | TSHRLMNATHRBSLC22A1SLC22A2 | |
| SCHEMBL18600561 | 0.85 | TSHR (0.44) | TSHRLMNATHRBSLC22A1SLC22A2 | |
| SCHEMBL4411318 | 0.81 | TSHR (0.40) | TSHRLMNATHRBSLC22A1SLC22A2 | |
| SCHEMBL7723281 | 0.80 | TSHR (0.38) | TSHRLMNATHRBALDH1A1ADRB2 | |
| SCHEMBL933335 | 0.79 | — | — | |
| SCHEMBL15385227 | 0.79 | — | — | |
| SCHEMBL704639 | 0.78 | — | — | |
| SCHEMBL853632 | 0.75 | — | — | |
| SCHEMBL703265 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051470-B | Process for preparing liquid composition | 住友化学株式会社 | 2020-11-10 | — | — | CN | disclosed |
| CN-111051470-A | Process for preparing liquid composition | 住友化学株式会社 | 2020-04-21 | — | — | CN | disclosed |
| WO-1991001994-A1 | 11β-SUBSTITUTED 16α,17α-METHYLENE-ESTRA-4,9-DIENE-3-ONES | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-02-21 | — | — | WO | disclosed |