Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.52 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21437392 | 0.99 | BACE1 (0.52) | BACE1EHMT2EPHX2EHMT1HTT | |
| SCHEMBL22919755 | 0.90 | EHMT2 (0.54) | BACE1EHMT2EHMT1HTTMAPT | |
| SCHEMBL22919765 | 0.90 | EHMT2 (0.56) | BACE1EHMT2EHMT1HTTMAPT | |
| Hydrochloric Acid SCHEMBL21437347 | 0.89 | EHMT2 (0.55) | BACE1EHMT2EHMT1HTTMAPT | |
| Hydrochloric Acid SCHEMBL21437364 | 0.89 | EHMT2 (0.53) | BACE1EHMT2EHMT1HTTMAPT | |
| SCHEMBL21437408 | 0.87 | BACE1 (0.53) | BACE1EHMT2EHMT1HTTMAPT | |
| SCHEMBL21450840 | 0.86 | BACE1 (0.46) | BACE1EHMT2EHMT1HTTMAPT | |
| SCHEMBL21450755 | 0.83 | BACE1 (0.54) | BACE1EHMT2EHMT1NPC1RAB9A | |
| SCHEMBL26451918 | 0.83 | EHMT2 (0.52) | BACE1EHMT2EHMT1HTTMAPT | |
| Hydrochloric Acid SCHEMBL21437366 | 0.83 | BACE1 (0.53) | BACE1EHMT2EHMT1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230138583-A1 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | OHIO STATE INNOVATION FOUNDATION | 2023-05-04 | — | — | US | disclosed |
| US-20230138583-A1 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | OHIO STATE INNOVATION FOUNDATION | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230138583-A1 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | ITGB3, ITGB2, ITGAM | BACE1 2983/4885EHMT2 1620/4885EPHX2 3239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.