Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13185171 | 0.83 | HTR2A (0.49) | CCR3BRD9CARM1PRMT6ACHE | |
| SCHEMBL8302417 | 0.83 | OPRM1 (0.51) | CCR3CARM1PRMT6ACHE | |
| SCHEMBL1119559 | 0.82 | GBA1 (0.43) | CCR3CCR5 | |
| SCHEMBL4040585 | 0.81 | LMNA (0.53) | CCR3BRD9CARM1PRMT6PRMT3 | |
| SCHEMBL8302415 | 0.81 | OPRM1 (0.51) | GRIN2B | |
| SCHEMBL578726 | 0.81 | SLC6A2 (0.52) | CCR3CCR5BRD9CARM1PRMT6 | |
| SCHEMBL2056158 | 0.81 | ALDH1A1 (0.61) | CCR3GRIN2B | |
| SCHEMBL327856 | 0.81 | CCR3 (0.66) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL20217376 | 0.80 | CARM1 (0.54) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL13498031 | 0.79 | MAOB (0.47) | KCNH2HTR2AHTR2CGRIN2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3549934-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2019-10-09 | — | — | EP | disclosed |