SCHEMBL21448240

Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@H](OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@@H](O)[C@H]3OC[PH](=O)O)[C@@H]2O)c(=O)[nH]1

nearest known ligand 0.61

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	RNASEL	Q05823	13/20	0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21511256	1.00	RNASEL (0.61)	RNASEL
SCHEMBL21448045	1.00	RNASEL (0.61)	RNASEL
SCHEMBL21454910	0.97	RNASEL (0.63)	RNASEL
SCHEMBL21454903	0.97	RNASEL (0.63)	RNASEL
SCHEMBL21454871	0.97	RNASEL (0.63)	RNASEL
SCHEMBL21454866	0.97	RNASEL (0.63)	RNASEL
SCHEMBL21448241	0.96	RNASEL (0.57)	RNASEL
SCHEMBL21511245	0.96	RNASEL (0.57)	RNASEL
SCHEMBL21448247	0.96	RNASEL (0.57)	RNASEL
SCHEMBL21454768	0.96	RNASEL (0.66)	RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019193543-A1	3'3'-CYCLIC DINUCLEOTIDES	INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ)	2019-10-10	—	—	WO	disclosed