Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 12/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21454866 | 1.00 | RNASEL (0.63) | RNASELADORA1 | |
| SCHEMBL21454903 | 1.00 | RNASEL (0.63) | RNASELADORA1 | |
| SCHEMBL21454871 | 1.00 | RNASEL (0.63) | RNASELADORA1 | |
| SCHEMBL21448240 | 0.97 | RNASEL (0.61) | RNASEL | |
| SCHEMBL21448045 | 0.97 | RNASEL (0.61) | RNASEL | |
| SCHEMBL21511256 | 0.97 | RNASEL (0.61) | RNASEL | |
| SCHEMBL21451380 | 0.96 | RNASEL (0.66) | RNASELADORA1 | |
| SCHEMBL21451234 | 0.96 | RNASEL (0.66) | RNASELADORA1 | |
| SCHEMBL21504314 | 0.96 | RNASEL (0.66) | RNASELADORA1 | |
| SCHEMBL21451368 | 0.96 | RNASEL (0.66) | RNASELADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149052-B2 | 2′3′-cyclic dinucleotides | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) | 2021-10-19 | — | — | US | disclosed |
| US-20190322695-A1 | 2'3'-CYCLIC DINUCLEOTIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR,V.V.I. (CZ) | 2019-10-24 | — | — | US | disclosed |
| WO-2019193542-A1 | 2'3'-CYCLIC DINUCLEOTIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) | 2019-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11149052-B2 | 2′3′-cyclic dinucleotides | STING1, MAVS, CGAS | RNASEL 1404/4885ADORA1 4032/4885 |
| US-20190322695-A1 | 2'3'-CYCLIC DINUCLEOTIDES | STING1, MAVS, CGAS | RNASEL 1439/4885ADORA1 4021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.