Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17986173 | 0.95 | KDM4E (0.55) | KDM4EALDH1A1NPSR1L3MBTL1MAPT | |
| SCHEMBL8209027 | 0.86 | KDM4E (0.68) | KDM4EALDH1A1NPSR1L3MBTL1MAPT | |
| SCHEMBL30218423 | 0.86 | KDM4E (0.68) | KDM4EALDH1A1NPSR1L3MBTL1MAPT | |
| SCHEMBL21044013 | 0.86 | KDM4E (0.68) | KDM4EALDH1A1NPSR1L3MBTL1MAPT | |
| SCHEMBL8211724 | 0.86 | KDM4E (0.68) | KDM4EALDH1A1NPSR1L3MBTL1MAPT | |
| SCHEMBL26969150 | 0.86 | KDM4E (0.68) | KDM4EALDH1A1NPSR1L3MBTL1MAPT | |
| SCHEMBL30811211 | 0.86 | KDM4E (0.68) | KDM4EALDH1A1NPSR1L3MBTL1MAPT | |
| SCHEMBL28895784 | 0.81 | ALDH1A1 (0.66) | KDM4EALDH1A1NPSR1L3MBTL1MAPT | |
| SCHEMBL2137893 | 0.81 | ALDH1A1 (0.68) | KDM4EALDH1A1NPSR1L3MBTL1MAPT | |
| SCHEMBL21043972 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1NPSR1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10441669-B2 | Multifunctional chelators, complexes, and compositions thereof, and methods of using same | ILLINOIS INSTITUTE OF TECHNOLOGY (US) | 2019-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10441669-B2 | Multifunctional chelators, complexes, and compositions thereof, and methods of using same | FECH, SLC40A1, TFRC | KDM4E 3507/4885ALDH1A1 4350/4885NPSR1 3872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.