Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653 | 0.86 | ALDH1A1 (0.55) | ALDH1A1TP53TRPA1CYP3A4MIF | |
| Hydrogen Sulfide SCHEMBL5079696 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TP53TRPA1CYP3A4MIF | |
| SCHEMBL3373294 | 0.80 | TP53 (0.46) | ALDH1A1TP53TRPA1CYP3A4MIF | |
| SCHEMBL10325242 | 0.78 | TRPA1 (0.48) | ALDH1A1TP53TRPA1CYP3A4MIF | |
| SCHEMBL5101986 | 0.77 | IDO1 (0.44) | ALDH1A1TP53HPGDKMT2AIDO1 | |
| SCHEMBL22272281 | 0.77 | TP53 (0.48) | ALDH1A1TP53TRPA1CYP3A4MIF | |
| SCHEMBL2776492 | 0.77 | TP53 (0.42) | ALDH1A1TP53TRPA1CYP3A4MIF | |
| SCHEMBL1885696 | 0.75 | MIF (0.54) | ALDH1A1TP53TRPA1MIFHPGD | |
| SCHEMBL8851885 | 0.75 | TAAR1 (0.40) | ALDH1A1LMNAIDO1KDM4E | |
| SCHEMBL3157505 | 0.75 | LOXL2 (0.42) | ALDH1A1CYP3A4HPGDHSD17B10LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 685 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220211701-A1 | TREATMENT OF CANCER UTILIZING AN IDENTIFIED ADENOSINE FINGERPRINT | ARCUS BIOSCIENCES, INC. (US) | 2022-07-07 | — | — | US | claimed |
| CN-114395005-A | Modulators of extracellular 5' -nucleotidase and uses thereof | 艾库斯生物科学有限公司 | 2022-04-26 | — | — | CN | claimed |
| EP-3947463-A1 | TREATMENT OF CANCER UTILIZING AN IDENTIFIED ADENOSINE FINGERPRINT | Arcus Biosciences, Inc. (US) | 2022-02-09 | — | — | EP | claimed |
| EP-3937964-A1 | TREATMENT OF ONCOGENE-DRIVEN CANCERS | Arcus Biosciences, Inc. (US) | 2022-01-19 | — | — | EP | claimed |
| CN-113874397-A | Treatment of cancer using identified adenosine fingerprints | 艾库斯生物科学有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-113795267-A | Oncogene driven treatment of cancer | 艾库斯生物科学有限公司 | 2021-12-14 | — | — | CN | claimed |
| EP-3761993-A1 | PARENTERALLY ADMINISTERED IMMUNE ENHANCING DRUGS | Arcus Biosciences, Inc. (US) | 2021-01-13 | — | — | EP | claimed |
| US-20200405629-A1 | PARENTERALLY ADMINISTERED IMMUNE ENHANCING DRUGS | ARCUS BIOSCIENCES, INC. | 2020-12-31 | — | — | US | claimed |
| CN-112004541-A | Immunopotentiating medicine for parenteral administration | 艾库斯生物科学有限公司 | 2020-11-27 | — | — | CN | claimed |
| WO-2020205527-A1 | TREATMENT OF CANCER UTILIZING AN IDENTIFIED ADENOSINE FINGERPRINT | ARCUS BIOSCIENCES, INC. (US) | 2020-10-08 | — | — | WO | claimed |
| EP-0011756-A2 | Pressure sensitive registration material | BASF Aktiengesellschaft (DE) | 1980-06-11 | — | — | EP | claimed |
| US-4132436-A | Recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1979-01-02 | — | — | US | claimed |
| US-4122089-A | Aminothiofluoran compounds, process for the production thereof, and recording elements containing the same | SANKIO CHEMICAL CO., LTD. (JP) | 1978-10-24 | — | — | US | claimed |
| US-4119777-A | BY OXIDATION OF A THIOAMIDE DERIVATIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1978-10-10 | — | — | US | claimed |
| US-4094877-A | SUBSTITUTED 3,3-DIPHENYLPHTHALIDES AS COLOR PRECURSORS | STERLING DRUG INC. (US) | 1978-06-13 | — | — | US | claimed |
| US-4049661-A | FIBER-REACTIVE | CIBA-GEIGY AG (CH) | 1977-09-20 | — | — | US | claimed |
| US-4042642-A | 1,3-BIS(MORPHOLINOTHIO)-IMIDAZOLIDINONE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-08-16 | — | — | US | claimed |
| US-4029597-A | AZO DYES HAVING A SULFONIC ACID OR CARBOXYL GROUP | E. MERCK A. G. (DT) | 1977-06-14 | — | — | US | claimed |
| US-4029598-A | AZO DYES HAVING A SULFONIC ACID OR CARBOXYL GROUP | E. MERCK A. G. (DT) | 1977-06-14 | — | — | US | claimed |
| US-3960857-A | Urea additives for sulfur vulcanizable polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-06-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200405629-A1 | PARENTERALLY ADMINISTERED IMMUNE ENHANCING DRUGS | NT5C2, ADA, ENTPD1 | ALDH1A1 1616/4885TP53 2623/4885TRPA1 4785/4885 |
| US-20220211701-A1 | TREATMENT OF CANCER UTILIZING AN IDENTIFIED ADENOSINE FINGERPRINT | NTPCR, ADORA2A, NT5C2 | ALDH1A1 630/4885TP53 34/4885TRPA1 4641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.