Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14127316 | 0.76 | POLB (0.67) | POLBKDM4EATMKMT2AMAPT | |
| SCHEMBL14495327 | 0.76 | ATM (0.65) | POLBKDM4EATMKMT2AMAPT | |
| SCHEMBL102971 | 0.73 | KDM4E (0.89) | POLBKDM4EATMKMT2AMAPT | |
| SCHEMBL16071127 | 0.73 | TSHR (0.56) | POLBKDM4EATMKMT2AMAPT | |
| SCHEMBL14392224 | 0.72 | POLB (0.53) | POLBKDM4EATMKMT2AMAPT | |
| SCHEMBL16795707 | 0.70 | TSHR (0.53) | POLBKDM4EATMKMT2AMAPT | |
| SCHEMBL12930767 | 0.70 | KDM4E (0.67) | POLBKDM4EATMKMT2AMAPT | |
| SCHEMBL3465063 | 0.69 | MEN1 (0.69) | POLBKMT2AMAPTLMNAMEN1 | |
| SCHEMBL14376022 | 0.69 | POLB (0.58) | POLBKDM4EATMKMT2AMAPT | |
| SCHEMBL29110815 | 0.69 | POLB (0.58) | POLBKDM4EATMKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019194556-A1 | NOVEL 6-HETEROARYLAMINO-2,4,5-TRIMETHYLPYRIDIN-3-OL COMPOUND, OR PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASES AND AUTOIMMUNE DISEASES COMPRISING SAME | 영남대학교 산학협력단 | 2019-10-10 | — | — | WO | disclosed |