Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.89 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.58 |
| ▸ | WNT3A | P56704 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14849222 | 0.94 | KDM4E (1.00) | KDM4ETSHRATMPOLBHPGD | |
| SCHEMBL10031401 | 0.94 | KDM4E (1.00) | KDM4ETSHRATMPOLBHPGD | |
| SCHEMBL14937523 | 0.94 | KDM4E (1.00) | KDM4ETSHRATMPOLBHPGD | |
| SCHEMBL13596352 | 0.92 | KDM4E (0.77) | KDM4ETSHRATMPOLBHPGD | |
| SCHEMBL3735582 | 0.92 | KDM4E (0.77) | KDM4ETSHRATMPOLBHPGD | |
| 3,4-Methylendioxy Acetophenone SCHEMBL137979 | 0.88 | KDM4E (0.71) | KDM4ETSHRHPGDCYP1A2CYP2C19 | |
| 3,4-Methylendioxy Acetophenone SCHEMBL29405437 | 0.88 | KDM4E (0.71) | KDM4ETSHRHPGDCYP1A2CYP2C19 | |
| 3,4-Methylendioxy Acetophenone SCHEMBL31108909 | 0.85 | KDM4E (0.67) | KDM4ETSHRATMPOLBHPGD | |
| SCHEMBL12930767 | 0.85 | KDM4E (0.67) | KDM4ETSHRATMPOLBHPGD | |
| SCHEMBL4824992 | 0.83 | NPSR1 (0.74) | KDM4ETSHRATMHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3354727-B1 | TRANSAMINASE POLYPEPTIDES | CODEXIS INC (US) | 2020-10-07 | — | — | EP | claimed |
| US-10052326-B1 | Antihepatotoxic agents | KING SAUD UNIVERSITY (SA) | 2018-08-21 | — | — | US | claimed |
| EP-3354727-A1 | TRANSAMINASE POLYPEPTIDES | Codexis, Inc. (US) | 2018-08-01 | — | — | EP | claimed |
| EP-2385983-B1 | TRANSAMINASE POLYPEPTIDES | CODEXIS INC (US) | 2017-12-20 | — | — | EP | claimed |
| CN-102797043-B | Medicinal molecular fragment library and construction process thereof | Tianli (Tianjin) Technology Co., Ltd. (CN) | 2015-11-25 | — | — | CN | claimed |
| CN-102797043-A | Medicinal molecular fragment library and construction method thereof | CBB NETWORK CO LTD | 2012-11-28 | — | — | CN | claimed |
| EP-2385983-A2 | TRANSAMINASE POLYPEPTIDES | Codexis, Inc. (US) | 2011-11-16 | — | — | EP | claimed |
| US-D646886-S1 | Tip of an umbrella | Pro Performance Sports, L.L.C. (US) | 2011-10-18 | — | — | US | claimed |
| US-20100209981-A1 | TRANSAMINASE POLYPEPTIDES | CODEXIS, INC. (US) | 2010-08-19 | — | — | US | claimed |
| WO-2010081053-A2 | TRANSAMINASE POLYPEPTIDES | CODEXIS, INC. (US) | 2010-07-15 | — | — | WO | claimed |
| WO-2008035904-A1 | METHOD FOR PROCESSING 4-SUBSTITUTED BENZOIC ACID DERIVATIVES HAVING 3, 4-METHYLENE- OR 3,4-ETHYLENEDIOXYBENZENE MOIETY AND THE USE OF THE SAME FOR ANTIAGING COSMETICS | AMOREPACIFIC CORPORATION (KR) | 2008-03-27 | — | — | WO | claimed |
| US-7078131-B2 | Polymeric sol electrolyte and lithium battery using the same | SAMSUNG SDI CO., LTD. (KR) | 2006-07-18 | — | — | US | claimed |
| US-20030059681-A1 | Polymeric sol electrolyte and lithium battery using the same | SAMSUNG SDI CO., LTD. (KR) | 2003-03-27 | — | — | US | claimed |
| US-20010031758-A1 | Substituted 9H-pyridino[2,3-b] indole and 9H-pyrimidino[4,5-b] indole derivatives: selective neuropeptide Y receptor ligands | NEUROGEN CORPORATION | 2001-10-18 | — | — | US | claimed |
| US-6221875-B1 | TREATING FEEDING DISORDERS, OBESITY, BULIMIA NERVOSA OR HYPERTENSION IN A MAMMAL | NEUROGEN CORPORATION | 2001-04-24 | — | — | US | claimed |
| US-6117223-A | Hot melt inks containing polyketones | XEROX CORPORATION (US) | 2000-09-12 | — | — | US | claimed |
| US-20260125378-A2 | Heterocyclic Compounds | BEONE MEDICINES I GMBH (CH) | 2026-05-07 | — | — | US | disclosed |
| US-20260028600-A1 | TRANSAMINASE POLYPEPTIDES | CODEXIS INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-4097671-A | 5-PHENYL-3,6-DIHYDRO-1,3,4-OXADIAZIN-2-ONE, THERMOPLASTIC POLYMER BLOWING AGENT | GENERAL ELECTRIC COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-3937841-A | AMINO-OXIME COMPOUNDS | U.S. PHILIPS CORPORATION (US) | 1976-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125378-A2 | Heterocyclic Compounds | NFATC1, CD4, MALT1 | KDM4E 1832/4885TSHR 362/4885ATM 3845/4885 |
| US-10052326-B1 | Antihepatotoxic agents | CYP4X1, CYP2E1, HRH2 | KDM4E 615/4885TSHR 1351/4885ATM 4281/4885 |
| US-20260028600-A1 | TRANSAMINASE POLYPEPTIDES | GOT1, OAT, PEPD | KDM4E 3487/4885TSHR 794/4885ATM 760/4885 |
| US-20010031758-A1 | Substituted 9H-pyridino[2,3-b] indole and 9H-pyrimidino[4,5-b] indole derivatives: selective neuropeptide Y receptor ligands | NPY1R, NPY2R, NPY5R | KDM4E 2474/4885TSHR 117/4885ATM 4355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.