Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074497 | 0.83 | MEN1 (0.62) | MEN1KMT2AALDH1A1MAPK1SRD5A2 | |
| SCHEMBL27481742 | 0.82 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1MAPK1SRD5A2 | |
| SCHEMBL16560481 | 0.82 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1MAPK1SRD5A2 | |
| SCHEMBL18650655 | 0.80 | MEN1 (0.59) | MEN1KMT2AALDH1A1MAPK1SRD5A2 | |
| 3,4-Methylendioxy Acetophenone SCHEMBL29405437 | 0.80 | KDM4E (0.71) | MEN1KMT2AALDH1A1MAPK1SRD5A2 | |
| SCHEMBL21451034 | 0.80 | MEN1 (0.59) | MEN1KMT2AALDH1A1MAPK1SRD5A2 | |
| SCHEMBL26604309 | 0.80 | MEN1 (0.59) | MEN1KMT2AALDH1A1MAPK1SRD5A2 | |
| 3,4-Methylendioxy Acetophenone SCHEMBL137979 | 0.80 | KDM4E (0.71) | MEN1KMT2AALDH1A1MAPK1SRD5A2 | |
| SCHEMBL16152423 | 0.79 | KMT2A (0.58) | MEN1KMT2AALDH1A1MAPK1SRD5A2 | |
| SCHEMBL19435741 | 0.78 | KMT2A (0.65) | MEN1KMT2AALDH1A1MAPK1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4212809-A | Process for the preparation of 5-(oxiranylmethyl)-1,3-benzodioxole | BAYER AKTIENGESELLSCHAFT (DE) | 1980-07-15 | — | — | US | claimed |
| WO-2024181177-A1 | COPOLYMER, POSITIVE RESIST COMPOSITION, AND RESIST PATTERN FORMATION METHOD | 日本ゼオン株式会社 | 2024-09-06 | — | — | WO | disclosed |
| CN-117867526-A | Preparation method of 2-deuterium-1, 2-diphenylethane derivative | 五邑大学 | 2024-04-12 | — | — | CN | disclosed |
| WO-2024059107-A1 | IKZF2 AND CK1-ALPHA DEGRADING COMPOUNDS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-03-21 | — | — | WO | disclosed |
| CN-117384071-A | Synthesis method of hydroxy thioether compound | 江南大学 | 2024-01-12 | — | — | CN | disclosed |
| EP-2527315-B1 | Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as Alzheimer's disease, type 2 diabetes and Parkinson's disease | PROTEOTECH INC (US) | 2014-03-19 | — | — | EP | disclosed |
| WO-2012054417-A1 | AMIDE DERIVATIVES OF BENZENE-SULFONANILIDE, PHARMACEUTICAL COMPOSITION THEREOF AND METHOD FOR CANCER TREATMENT USING THE SAME | CLEVELAND STATE UNIVERSITY (US) | 2012-04-26 | — | — | WO | disclosed |
| US-20100240656-A1 | COMPOUNDS AS HSP90 INHIBITORS | ORYZON GENOMICS, S.A. (ES) | 2010-09-23 | — | — | US | disclosed |
| EP-2183221-A1 | NEW COMPOUNDS AS HSP90 INHIBITORS | Crystax Pharmaceuticals S.L. (ES) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009007399-A1 | NEW COMPOUNDS AS HSP90 INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2009-01-15 | — | — | WO | disclosed |
| US-6025310-A | RETAINING STABILITY FREE OF HYDROLYSIS FOR PROLONGED PERIOD OF TIME, COMPATIBLE WITH ORGANIC LUBRICANTS HAVING BENZENE RING AND PHOSPHAZINE RING | KUBOTA CORPORATION (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0614869-B1 | Hydrogenolytic reduction of peroxidic ozonolysis compounds | CHEMIE LINZ GMBH (AT) | 1997-05-21 | — | — | EP | disclosed |
| US-5543560-A | Hydrogenolytic reduction of peroxidic ozonolysis products | CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) | 1996-08-06 | — | — | US | disclosed |
| US-5475024-A | Useful in treating liver disease | EISAI CO., LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| EP-0614869-A1 | Hydrogenolytic reduction of peroxidic ozonolysis compounds | DSM Chemie Linz GmbH (AT) | 1994-09-14 | — | — | EP | disclosed |
| US-5292901-A | Benzodioxole derivatives | EISAI CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0281098-B1 | BENZODIOXOLE DERIVATIVES, COMPOSITIONS COMPRISING THE SAME, AND THE USE OF THE SAME FOR THE MANUFACTURE OF MEDICAMENTS | Eisai Co., Ltd. (JP) | 1992-11-25 | — | — | EP | disclosed |
| US-5110956-A | Liver disorders | EISAI CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |
| CN-88101155-A | The preparation of benzo benzodioxole derivatives and application thereof | — | 1988-09-28 | — | — | CN | disclosed |
| EP-0281098-A1 | Benzodioxole derivatives, compositions comprising the same, and the use of the same for the manufacture of medicaments | Eisai Co., Ltd. (JP) | 1988-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240656-A1 | COMPOUNDS AS HSP90 INHIBITORS | HSP90AB1, HSP90AB2P, HSP90AA1 | MEN1 4594/4885KMT2A 4661/4885ALDH1A1 1875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.