SCHEMBL21451721

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21717474	0.89	CHUK (0.50)	PARP1SMN1; SMN2CYP2A6LMNAF11
	SCHEMBL21448261	0.89	ALDH1A1 (0.50)	PARP1TP53SMN1; SMN2CYP2A6LMNA
	SCHEMBL30180882	0.89	ALDH1A1 (0.50)	PARP1TP53SMN1; SMN2CYP2A6LMNA
	SCHEMBL21448386	0.87	AHR (0.57)	SMN1; SMN2CYP2A6LMNAHPGDALDH1A1
	SCHEMBL30180942	0.87	AHR (0.57)	SMN1; SMN2CYP2A6LMNAHPGDALDH1A1
	SCHEMBL30180806	0.87	AHR (0.57)	SMN1; SMN2CYP2A6LMNAHPGDALDH1A1
	SCHEMBL21448183	0.87	AHR (0.57)	SMN1; SMN2CYP2A6LMNAHPGDALDH1A1
	SCHEMBL2141394	0.83	PARP1 (0.61)	PARP1TP53SMN1; SMN2LMNAHPGD
	SCHEMBL6009587	0.83	PARP1 (0.65)	PARP1TP53SMN1; SMN2LMNAHPGD
	SCHEMBL31167250	0.83	PARP1 (0.65)	PARP1TP53SMN1; SMN2LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.