Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 10/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21452549 | 1.00 | PDE2A (0.42) | PDE2ARORCFAAHTRPV1MAPT | |
| SCHEMBL21452178 | 1.00 | PDE2A (0.42) | PDE2ARORCFAAHTRPV1MAPT | |
| SCHEMBL21452392 | 0.88 | RORC (0.43) | RORCFAAHMAPTSLC6A4 | |
| SCHEMBL21452427 | 0.86 | SLC6A4 (0.42) | FAAHTRPV1MAPTSLC6A4SLC6A3 | |
| SCHEMBL26451008 | 0.85 | SLC6A4 (0.40) | SLC6A4 | |
| SCHEMBL21452447 | 0.83 | PDE2A (0.43) | PDE2ARORC | |
| SCHEMBL23001555 | 0.83 | PDE2A (0.39) | PDE2ARORCMAPT | |
| SCHEMBL21452417 | 0.83 | PDE2A (0.39) | PDE2ARORCMAPT | |
| SCHEMBL21452021 | 0.82 | EGLN2 (0.35) | — | |
| SCHEMBL25380609 | 0.82 | PDE2A (0.46) | PDE2AFAAHTRPV1SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250177324-A1 | AMINOKETONE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI ZHIGEN PHARMACEUTICAL & TECHNOLOGY CO. LTD. (CN) | 2025-06-05 | — | — | US | disclosed |
| EP-4488260-A1 | NEW AMINOKETONE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Zhigen Pharmaceutical & Technology Co. Ltd. (CN) | 2025-01-08 | — | — | EP | disclosed |
| CN-116730853-A | Novel aminoketone compound and preparation method and application thereof | 上海致根医药科技有限公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2023165575-A1 | NEW AMINOKETONE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海致根医药科技有限公司 | 2023-09-07 | — | — | WO | disclosed |
| US-20210171487-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI JIANHE PHARMACEUTICAL & TECHNOLOGY CO. LTD. (CN) | 2021-06-10 | — | — | US | disclosed |
| EP-3778579-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jianhe Pharmaceutical & Technology Co. Ltd. (CN) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019192602-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海键合医药科技有限公司 | 2019-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250177324-A1 | AMINOKETONE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | AADAT, ALDH7A1, AASDHPPT | PDE2A 3513/4885RORC 1989/4885FAAH 605/4885 |
| US-20210171487-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP4F11, PAH, COMT | PDE2A 4338/4885RORC 165/4885FAAH 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.