Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.32 |
| ▸ | RORC | P51449 | 4/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21451947 | 0.88 | DPP8 (0.33) | DPP8DPP9BDKRB1RORCNFKB1 | |
| SCHEMBL21452126 | 0.84 | RORC (0.41) | DPP8DPP9RORCNFKB1NFKB2 | |
| SCHEMBL23003282 | 0.84 | RORC (0.41) | DPP8DPP9RORCNFKB1NFKB2 | |
| SCHEMBL21452458 | 0.81 | HDAC4 (0.36) | DPP8DPP9BDKRB1RORCNFKB1 | |
| SCHEMBL25381097 | 0.81 | HDAC4 (0.36) | DPP8DPP9BDKRB1RORCNFKB1 | |
| SCHEMBL21452373 | 0.78 | CCR2 (0.38) | BRD4CREBBPDDB1CRBNMEN1 | |
| SCHEMBL23001555 | 0.78 | PDE2A (0.39) | RORCMAPK1 | |
| SCHEMBL21452417 | 0.78 | PDE2A (0.39) | RORCMAPK1 | |
| SCHEMBL21452463 | 0.78 | DPP8 (0.33) | DPP8DPP9BDKRB1RORCNFKB1 | |
| SCHEMBL21452404 | 0.77 | MEN1 (0.42) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778579-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jianhe Pharmaceutical & Technology Co. Ltd. (CN) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019192602-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海键合医药科技有限公司 | 2019-10-10 | — | — | WO | disclosed |