Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MASP2 | O00187 | 1/20 | 0.53 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | FABP6 | P51161 | 1/20 | 0.50 |
| ▸ | TYMS | P04818 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL16011374 | 0.98 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL5679606 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL30727335 | 0.84 | BACE1 (0.61) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL2725820 | 0.84 | BACE1 (0.61) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL5681861 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL4483413 | 0.79 | NOS1 (0.44) | ALDH1A1PABPC1BACE1PDPK1JAK2 | |
| SCHEMBL1170673 | 0.79 | PDPK1 (0.51) | ALDH1A1PABPC1BACE1PDPK1MMP2 | |
| SCHEMBL29449363 | 0.79 | MEN1 (0.57) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL118057 | 0.79 | MEN1 (0.57) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| Hydrochloric Acid SCHEMBL6621838 | 0.78 | MEN1 (0.55) | ALDH1A1MEN1KMT2AMASP2NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10292390-B2 | Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-05-21 | — | — | US | claimed |
| US-20130136782-A1 | Inhibition and Dispersion of Bacterial Biofilms with 2-Aminobenzimidazole Derivatives | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2013-05-30 | — | — | US | claimed |
| US-4496727-A | ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | claimed |
| US-4385174-A | FOR PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | claimed |
| US-4349671-A | Process for the production of metal complexes of isoindoline azines | CIBA-GEIGY CORPORATION (US) | 1982-09-14 | — | — | US | claimed |
| CN-120058739-A | Cycloalkyl-or haloalkyl-containing compounds | 正大天晴药业集团股份有限公司 | 2025-05-30 | — | — | CN | disclosed |
| US-20250034165-A1 | COMPOUND CONTAINING CYCLOALKYL OR HALOALKYL | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2025-01-30 | — | — | US | disclosed |
| EP-4442690-A1 | COMPOUND CONTAINING CYCLOALKYL OR HALOALKYL | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2024-10-09 | — | — | EP | disclosed |
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-07-18 | — | — | US | disclosed |
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-07-18 | — | — | US | disclosed |
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-07-18 | — | — | US | disclosed |
| CN-118265713-A | Cycloalkyl-or haloalkyl-containing compounds | 正大天晴药业集团股份有限公司 | 2024-06-28 | — | — | CN | disclosed |
| EP-1620413-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004098494-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-11-18 | — | — | WO | disclosed |
| US-4237286-A | COLORING PLASTICS AND LACQUERS IN YELLOW TO RED SHADES | CIBA-GEIGY CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |
| US-4237292-A | SHADES OF YELLOW TO RED FOR PLASTICS AND LACQUERS | CIBA-GEIGY CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |
| US-4237293-A | COLORFAST SHADES OF YELLOW TO RED FOR PLASTICS AND LACQUERS | CIBA-GEIGY CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |
| US-4132708-A | Metal complexes of azomethines and process for their manufacture | CIBA-GEIGY CORPORATION (US) | 1979-01-02 | — | — | US | disclosed |
| US-4111947-A | DYES, PLASTICS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |
| US-4022770-A | COLORING | CIBA-GEIGY CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130136782-A1 | Inhibition and Dispersion of Bacterial Biofilms with 2-Aminobenzimidazole Derivatives | FLNB, BRI3BP, CCNI | ALDH1A1 1841/4885MEN1 3710/4885KMT2A 1202/4885 |
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | KLK5, KLK1, KLKB1 | ALDH1A1 1532/4885MEN1 3113/4885KMT2A 1480/4885 |
| US-10292390-B2 | Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives | FLNB, BRI3BP, CCNI | ALDH1A1 1841/4885MEN1 3710/4885KMT2A 1202/4885 |
| US-20250034165-A1 | COMPOUND CONTAINING CYCLOALKYL OR HALOALKYL | KRAS, HRAS, VHL | ALDH1A1 1265/4885MEN1 744/4885KMT2A 3640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.