Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | FABP6 | P51161 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214526 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL5681861 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL3827667 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| Bromide SCHEMBL16011374 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL5679426 | 0.83 | FABP6 (0.53) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL16848371 | 0.83 | JAK2 (0.50) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL5679783 | 0.83 | BACE1 (0.59) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL5679441 | 0.83 | MASP2 (0.47) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL5683290 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL20982568 | 0.79 | MMP2 (0.57) | ALDH1A1MEN1KMT2AMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620413-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004098494-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-11-18 | — | — | WO | disclosed |