Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 4/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 5/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21434107 | 0.86 | PDE2A (0.40) | KMT2ARETPDE2AEPHX2 | |
| SCHEMBL21452862 | 0.71 | KMT2A (0.44) | CYP11B2CYP11B1KMT2APDE2A | |
| SCHEMBL21433923 | 0.69 | SMPD3 (0.46) | EPHX2 | |
| SCHEMBL21434001 | 0.67 | ITGB2 (0.58) | CYP11B2CYP11B1EPHX2 | |
| SCHEMBL3878855 | 0.67 | GALR2 (0.48) | EPHX2 | |
| SCHEMBL6990041 | 0.67 | MAPT (0.63) | KMT2ACYP2C9 | |
| SCHEMBL6990035 | 0.67 | MAPT (0.63) | KMT2ACYP2C9 | |
| SCHEMBL8514715 | 0.66 | RARA (0.46) | KMT2A | |
| SCHEMBL21452774 | 0.65 | ITGB2 (0.54) | KIF11 | |
| SCHEMBL21434071 | 0.65 | TDP1 (0.46) | KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019193516-A2 | SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-10-10 | — | — | WO | disclosed |