Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 14/20 | 0.46 |
| ▸ | RARB | P10826 | 13/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 13/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8512735 | 0.86 | GPR119 (0.48) | RARARARBKMT2A | |
| SCHEMBL12959456 | 0.83 | RARB (0.59) | RARARARBRARGRXRAABCB1 | |
| SCHEMBL8514041 | 0.82 | RARB (0.46) | RARARARBRARGRXRAABCB1 | |
| SCHEMBL9612709 | 0.81 | KMT2A (0.47) | RARARARBKMT2ARARG | |
| Trifluoroacetic Acid SCHEMBL8537644 | 0.81 | HRH4 (0.43) | RARARARBKMT2ARARGRXRA | |
| SCHEMBL2015482 | 0.76 | RARA (0.50) | RARARARBRARG | |
| SCHEMBL8514584 | 0.74 | RARB (0.56) | RARARARBKMT2ARARGRXRA | |
| SCHEMBL27973420 | 0.73 | RARA (0.47) | RARARARBRARG | |
| SCHEMBL27872046 | 0.72 | RARA (0.46) | RARARARBRARG | |
| SCHEMBL11963431 | 0.70 | GBA1 (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069852-A1 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF SPHINGOSINE KINASE | ALMAC DISCOVERY LIMITED (GB) | 2012-05-31 | — | — | WO | disclosed |