Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | AMPD2 | Q01433 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17426062 | 0.84 | ALDH1A1 (0.48) | GAAELANEAMPD2LMNAALDH1A1 | |
| SCHEMBL30748924 | 0.83 | LMNA (0.46) | GAAELANEAMPD2LMNAALDH1A1 | |
| SCHEMBL21438830 | 0.81 | GAA (0.43) | GAAELANEAMPD2LMNAALDH1A1 | |
| SCHEMBL21468773 | 0.80 | GAA (0.42) | GAAELANEAMPD2LMNAALDH1A1 | |
| SCHEMBL21245089 | 0.80 | AMPD2 (0.48) | GAAELANEAMPD2LMNAALDH1A1 | |
| SCHEMBL21439191 | 0.80 | LMNA (0.44) | GAAELANEAMPD2LMNAALDH1A1 | |
| SCHEMBL21468553 | 0.79 | KMT2A (0.45) | GAAELANEAMPD2LMNAALDH1A1 | |
| SCHEMBL9073520 | 0.78 | AMPD2 (0.49) | AMPD2LMNA | |
| SCHEMBL16400522 | 0.77 | GAA (0.42) | GAAELANEAMPD2LMNAALDH1A1 | |
| SCHEMBL17063254 | 0.76 | AMPD2 (0.44) | ELANEAMPD2LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195739-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | ABELA ALEXANDER RUSSELL (US) | 2019-10-10 | — | — | WO | disclosed |