Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.56 |
| ▸ | DUT | P33316 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31559529 | 0.82 | ADORA2A (0.38) | GLSDUTADORA2AADORA2BKMO | |
| SCHEMBL2149044 | 0.82 | ADORA2A (0.38) | GLSDUTADORA2AADORA2BKMO | |
| SCHEMBL19597355 | 0.79 | GLS (0.66) | GLSADORA2AADORA2BCHRM2CHRM1 | |
| SCHEMBL24088424 | 0.75 | REN (0.33) | GLSCNR1CNR2L3MBTL1 | |
| SCHEMBL21855708 | 0.75 | MEN1 (0.47) | CNR1CNR2L3MBTL1 | |
| SCHEMBL5591649 | 0.75 | DUT (0.42) | GLSDUTADORA2AADORA2BKMO | |
| SCHEMBL19597231 | 0.74 | GLS (0.59) | GLSADORA2AADORA2BPDE5ACHRM2 | |
| SCHEMBL19596918 | 0.74 | GLS (0.72) | GLSADORA2AADORA2BL3MBTL1KMO | |
| SCHEMBL13674332 | 0.74 | DUT (0.39) | GLSDUTCNR1CNR2SLC16A3 | |
| SCHEMBL4256101 | 0.74 | GLS (0.62) | GLSMPOCNR1CNR2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344494-A1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | Signal Pharmaceuticals, LLC (US) | 2011-07-20 | — | — | EP | disclosed |