SCHEMBL21453776

SCHEMBL21453776

c1ccc(-c2ccc3c(c2)c2cc(-c4ccccc4)cc4c5ccccc5c5cccc6sc7cccc(c7c65)n3c42)cc1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSPO P30536 2/20 0.34
PIK3CA P42336 1/20 0.31
PI4KA P42356 1/20 0.31
PI4KB Q9UBF8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21454246 0.96 TSPO (0.33) TSPOPIK3CAPI4KAPI4KB
SCHEMBL21453775 0.96 TSPO (0.34) TSPOPIK3CAPI4KAPI4KB
SCHEMBL21454230 0.95 TSPO (0.38) TSPOPIK3CAPI4KAPI4KB
SCHEMBL21453616 0.95 KDM4E (0.31) TSPO
SCHEMBL21454229 0.91 TSPO (0.38) TSPOPIK3CAPI4KAPI4KB
SCHEMBL21454231 0.91 KDM4E (0.33) TSPOPIK3CAPI4KAPI4KB
SCHEMBL21453491 0.90
SCHEMBL21453490 0.90 KDM4E (0.30)
SCHEMBL21453779 0.90 TSPO (0.35) TSPO
SCHEMBL21454105 0.89 KDM4E (0.36) TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L TSPO 136/4885PIK3CA 3855/4885PI4KA 2703/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L TSPO 136/4885PIK3CA 3855/4885PI4KA 2703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.