SCHEMBL21453797

SCHEMBL21453797

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccc5c(c4)c4ccc6sc7cccc8c9ccccc9c9ccccc9n5c4c6c78)c3)n2)cc1

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 1/20 0.30
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21454088 0.99 TSPO (0.31) NPY5R
SCHEMBL21454090 0.98 NPY5R (0.31) NPY5RKDM4ETSHRHSD17B10
SCHEMBL21454087 0.97 NPY5R (0.31) NPY5RKDM4ETSHRHSD17B10
SCHEMBL26246285 0.94 HSD17B1 (0.32) KDM4EHSD17B10
SCHEMBL21454113 0.94 NPY5R (0.32) NPY5RKDM4ETSHRHSD17B10
SCHEMBL21453802 0.93 MEN1 (0.33) KDM4E
SCHEMBL21453829 0.93
SCHEMBL26246278 0.93 KDM4E (0.31) KDM4ETSHRHSD17B10
SCHEMBL21454071 0.93 TSPO (0.33) NPY5RKDM4ETSHRHSD17B10
SCHEMBL21453822 0.92 ADORA2A (0.30) KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L NPY5R 3583/4885KDM4E 3723/4885TSHR 4332/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L NPY5R 3583/4885KDM4E 3723/4885TSHR 4332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.