SCHEMBL21454047

SCHEMBL21454047

c1ccc2c(c1)sc1cc(-c3ccc4c(c3)c3cccc5c6ccccc6c6ccccc6c6ccccc6n4c53)ccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
MAPT P10636 4/20 0.41
HPGD P15428 3/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
GPR3 P46089 1/20 0.39
POLB P06746 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
ALOX5 P09917 1/20 0.33
TSPO P30536 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALKBH5 Q6P6C2 1/20 0.30
FTO Q9C0B1 1/20 0.30
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21454159 0.93 ALDH1A1 (0.38) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL21453752 0.93 GPR3 (0.40) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL20465340 0.92 GPR3 (0.41) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL21453624 0.91 ALDH1A1 (0.36) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL21473040 0.91 ALDH1A1 (0.38) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL21453666 0.90 ALDH1A1 (0.35) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL20465309 0.88 ALDH1A1 (0.32) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL16850728 0.88 TSPO (0.38) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL16850716 0.88 TSPO (0.38) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL21454251 0.88 ALDH1A1 (0.33) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L ALDH1A1 802/4885MAPT 2041/4885HPGD 830/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L ALDH1A1 802/4885MAPT 2041/4885HPGD 830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.