Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.75 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.66 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.61 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10099575 | 0.87 | NR1H4 (0.84) | HDAC6HDAC1HDAC2HDAC8EPHX2 | |
| SCHEMBL11900090 | 0.87 | HDAC6 (0.85) | HDAC6HDAC1HDAC2HDAC8EPHX2 | |
| SCHEMBL457082 | 0.87 | HDAC6 (0.79) | HDAC6HDAC1HDAC2HDAC8EPHX2 | |
| SCHEMBL3454347 | 0.86 | HDAC6 (0.70) | HDAC6HDAC1HDAC2HDAC8EPHX2 | |
| SCHEMBL28839185 | 0.86 | HDAC6 (0.70) | HDAC6HDAC1HDAC2HDAC8EPHX2 | |
| SCHEMBL2829167 | 0.86 | HDAC6 (1.00) | HDAC6HDAC1HDAC2HDAC8EPHX2 | |
| SCHEMBL18422592 | 0.85 | CYP1A2 (0.55) | HDAC6HDAC1HDAC2HDAC8EPHX2 | |
| SCHEMBL29184442 | 0.85 | HDAC6 (0.76) | HDAC6HDAC1HDAC2HDAC8EPHX2 | |
| Hydrochloric Acid SCHEMBL3757721 | 0.85 | HDAC6 (0.76) | HDAC6HDAC1HDAC2HDAC8EPHX2 | |
| SCHEMBL28918342 | 0.84 | HDAC1 (0.79) | HDAC6HDAC1HDAC2HDAC8EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806503-A | Selective histone deacetylase inhibitor as well as preparation method and application thereof | 中国海洋大学 | 2023-03-17 | — | — | CN | claimed |
| CN-115806503-B | Selective histone deacetylase inhibitor and preparation method and application thereof | 中国海洋大学 | 2025-03-07 | — | — | CN | disclosed |
| CN-115806503-A | Selective histone deacetylase inhibitor as well as preparation method and application thereof | 中国海洋大学 | 2023-03-17 | — | — | CN | disclosed |
| US-10870618-B2 | Histone deacetylase inhibitors and uses thereof | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2020-12-22 | — | — | US | disclosed |
| US-20190308932-A1 | HISTONE DEACETYLASE INHIBITORS AND USES THEREOF | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2019-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10870618-B2 | Histone deacetylase inhibitors and uses thereof | HDAC1, HDAC5, HDAC3 | HDAC6 8/4885HDAC1 1/4885HDAC2 7/4885 |
| US-20190308932-A1 | HISTONE DEACETYLASE INHIBITORS AND USES THEREOF | HDAC1, HDAC5, HDAC3 | HDAC6 8/4885HDAC1 1/4885HDAC2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.