Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24104176 | 0.94 | KDM4E (0.38) | KDM4EATML3MBTL1CHEK2SIRT2 | |
| SCHEMBL21942051 | 0.92 | KDM4E (0.37) | KDM4EATML3MBTL1CHEK2SIRT2 | |
| SCHEMBL19655277 | 0.90 | KDM4E (0.38) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL21454964 | 0.89 | L3MBTL1 (0.44) | KDM4EATML3MBTL1PTGER4CASP1 | |
| SCHEMBL19653888 | 0.89 | SIRT2 (0.35) | KDM4EATML3MBTL1CHEK2SIRT2 | |
| SCHEMBL19655164 | 0.87 | SIRT2 (0.35) | KDM4EATML3MBTL1CHEK2SIRT2 | |
| SCHEMBL21716203 | 0.86 | HCRTR1 (0.31) | — | |
| SCHEMBL21716212 | 0.86 | HCRTR1 (0.31) | — | |
| SCHEMBL21213312 | 0.86 | L3MBTL1 (0.43) | KDM4EATML3MBTL1PTGER4CASP1 | |
| SCHEMBL24104941 | 0.85 | PLA2G2A (0.37) | KDM4EL3MBTL1CHEK2CASP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019194481-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2019-10-10 | — | — | WO | disclosed |