Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19655228 | 0.89 | KDM4E (0.34) | SIRT2SIRT1CHEK2KDM4EL3MBTL1 | |
| SCHEMBL24104176 | 0.88 | KDM4E (0.38) | SIRT2SIRT1CHEK2KDM4EL3MBTL1 | |
| SCHEMBL21454969 | 0.87 | KDM4E (0.37) | SIRT2SIRT1CHEK2KDM4EL3MBTL1 | |
| SCHEMBL19655184 | 0.86 | HSD17B10 (0.37) | KDM4EL3MBTL1CASP1HSD17B10NPC1 | |
| SCHEMBL19655130 | 0.86 | CHEK2 (0.33) | CHEK2MERTK | |
| SCHEMBL19653888 | 0.85 | SIRT2 (0.35) | SIRT2SIRT1CHEK2KDM4EL3MBTL1 | |
| SCHEMBL21942051 | 0.84 | KDM4E (0.37) | SIRT2SIRT1CHEK2KDM4EL3MBTL1 | |
| SCHEMBL19655277 | 0.84 | KDM4E (0.38) | SIRT2SIRT1KDM4EL3MBTL1ATM | |
| SCHEMBL24848686 | 0.84 | SIRT2 (0.33) | SIRT2SIRT1CHEK2KDM4EL3MBTL1 | |
| SCHEMBL19655161 | 0.84 | L3MBTL1 (0.39) | KDM4EL3MBTL1ATMCASP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10840458-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-11-17 | — | — | US | disclosed |
| US-20170346022-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2017-11-30 | — | — | US | disclosed |
| US-20170346022-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170346022-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | PDXK, MT-ND4L, PNPO | SIRT2 2200/4885SIRT1 2303/4885CHEK2 2069/4885 |
| US-10840458-B2 | Organic electroluminescent materials and devices | PDXK, MT-ND4L, PNPO | SIRT2 2200/4885SIRT1 2303/4885CHEK2 2069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.