⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8724212 | 0.97 | — | — | |
| SCHEMBL7005378 | 0.89 | TSHR (0.42) | — | |
| SCHEMBL7009496 | 0.80 | ALDH1A1 (0.42) | — | |
| SCHEMBL153943 | 0.75 | TSHR (0.67) | — | |
| SCHEMBL12467721 | 0.73 | HSD17B10 (0.44) | — | |
| Bromide SCHEMBL7630752 | 0.72 | TSHR (0.62) | — | |
| Hydrochloric Acid SCHEMBL2801770 | 0.72 | TSHR (0.62) | — | |
| Hydrochloric Acid SCHEMBL6241253 | 0.72 | TSHR (0.62) | — | |
| Water SCHEMBL486305 | 0.71 | — | — | |
| SCHEMBL4672020 | 0.71 | ATM (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4202 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125602-A1 | SALTS AND SOLID FORMS OF A COMPOUND HAVING GLP-1 AGONIST ACTIVITY | GASHERBRUM BIO, INC. (US) | 2024-06-20 | — | — | WO | claimed |
| CN-117143158-A | Cyclic palladium catalyst precursor, cyclic palladium catalyst, preparation method and application | 宁夏中星显示材料有限公司 | 2023-12-01 | — | — | CN | claimed |
| CN-115745995-A | ATR inhibitors and uses thereof | 苏州浦合医药科技有限公司 | 2023-03-07 | — | — | CN | claimed |
| CN-113024342-B | Method for regio-and stereoselectively synthesizing (E) -2,4, 4-trisubstituted conjugated diene | 温州大学 | 2022-06-24 | — | — | CN | claimed |
| CN-113024341-B | Method for regio-and stereoselectively synthesizing (E, E) -1,4, 4-trisubstituted conjugated diene | 温州大学 | 2022-05-20 | — | — | CN | claimed |
| EP-3997083-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | Idorsia Pharmaceuticals Ltd (CH) | 2022-05-18 | — | — | EP | claimed |
| CN-114127066-A | Inhibitors of indoleamine 2, 3-dioxygenase and/or tryptophan 2, 3-dioxygenase | 爱杜西亚药品有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-105980386-B | Pyrazolo compounds and uses thereof | 基因泰克公司 | 2021-08-13 | — | — | CN | claimed |
| US-11046662-B2 | 2-aryl-4-hydroxy-1,3-thiazole derivatives useful as TRPM8-inhibitors in treatment of neuralgia, pain, COPD and asthma | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2021-06-29 | — | — | US | claimed |
| EP-3201208-B1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-03-24 | — | — | EP | claimed |
| EP-0071370-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | ICI PHARMA (FR) | 1983-02-09 | — | — | EP | claimed |
| EP-0032856-B1 | 2,3-DIHYDROIMIDAZO (1,2-B) PYRIDAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE | SYNTHELABO (FR) | 1983-02-09 | — | — | EP | claimed |
| EP-0064707-A1 | 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-11-17 | — | — | EP | claimed |
| US-4353903-A | 2,3-Dihydro-imidazo[1,2-b]pyridazine derivatives, their preparation and use in treatment of depression | SYNTHELABO (FR) | 1982-10-12 | — | — | US | claimed |
| US-4332809-A | ANTIALLERGENS | TANABE SEIYAKU CO., LTD. (JP) | 1982-06-01 | — | — | US | claimed |
| US-4321207-A | Process for preparing triarylmethane dyes | AMERICAN CYANAMID COMPANY (US) | 1982-03-23 | — | — | US | claimed |
| EP-0034349-A2 | Novel pyridinecarboxamide derivatives, a process for the preparation thereof, the use of said derivatives and a pharmaceutical composition containing same | Tanabe Seiyaku Co., Ltd. (JP) | 1981-08-26 | — | — | EP | claimed |
| EP-0032856-A1 | 2,3-Dihydroimidazo (1,2-b) pyridazine derivatives, process for their preparation and their therapeutical use | SYNTHELABO (FR) | 1981-07-29 | — | — | EP | claimed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | claimed |
| US-4214909-A | SESQUITERPENE ALCOHOLS AND CARBOXYLIC ACID ESTERS THEREOF | KURARAY CO., LTD. (JP) | 1980-07-29 | — | — | US | claimed |