Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 4/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 3/20 | 0.34 |
| ▸ | TPSB2 | P20231 | 3/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24199900 | 0.84 | CFD (0.39) | CFDF10F2MRGPRX4F11 | |
| SCHEMBL21455660 | 0.83 | PDCD1 (0.38) | CFDMRGPRX4TBXAS1 | |
| SCHEMBL24200348 | 0.83 | CFD (0.39) | CFDF10F2MRGPRX4F11 | |
| SCHEMBL21455140 | 0.78 | TBXAS1 (0.39) | CFDCYP4F2CYP4A11LMNAL3MBTL1 | |
| SCHEMBL21455146 | 0.78 | CFD (0.37) | CFDF11TPSB2PLGPLAU | |
| SCHEMBL21455682 | 0.75 | TBXAS1 (0.44) | CYP4F2CYP4A11L3MBTL1TBXAS1 | |
| SCHEMBL24200155 | 0.74 | MRGPRX4 (0.35) | CFDMRGPRX4PPARGPPARAL3MBTL1 | |
| SCHEMBL21455351 | 0.73 | CFD (0.43) | CFDF10F2F11TPSB2 | |
| SCHEMBL24200223 | 0.73 | TBXAS1 (0.40) | CYP4F2CYP4A11L3MBTL1TBXAS1 | |
| SCHEMBL24200167 | 0.73 | TBXAS1 (0.38) | CYP4F2CYP4A11LMNAL3MBTL1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195720-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |