Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24200167 | 0.91 | TBXAS1 (0.38) | TBXAS1PKML3MBTL1LMNACYP4F2 | |
| SCHEMBL21455682 | 0.85 | TBXAS1 (0.44) | TBXAS1PKML3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL24200223 | 0.83 | TBXAS1 (0.40) | TBXAS1PKML3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL21455527 | 0.80 | TBXAS1 (0.35) | TBXAS1PKML3MBTL1LMNACYP4F2 | |
| SCHEMBL21561862 | 0.80 | TBXAS1 (0.40) | TBXAS1PKML3MBTL1LMNACYP4F2 | |
| SCHEMBL24200196 | 0.79 | TBXAS1 (0.39) | TBXAS1PKML3MBTL1LMNACYP4F2 | |
| SCHEMBL21455146 | 0.79 | CFD (0.37) | TBXAS1L3MBTL1LMNATRPM8CFD | |
| SCHEMBL21455151 | 0.78 | CFD (0.38) | TBXAS1L3MBTL1LMNACYP4F2CYP4A11 | |
| SCHEMBL23229004 | 0.77 | TBXAS1 (0.47) | TBXAS1PKML3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL7888801 | 0.76 | TBXAS1 (0.49) | TBXAS1PKML3MBTL1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195720-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |