Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25917934 | 0.80 | L3MBTL1 (0.37) | DPP4LMNAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL24200078 | 0.79 | L3MBTL1 (0.35) | L3MBTL1ALDH1A1HPGDCFDPARP14 | |
| SCHEMBL24199931 | 0.73 | CFD (0.42) | CFD | |
| SCHEMBL24200255 | 0.72 | KDM4E (0.36) | DPP4MAPTMRGPRX4ALDH1A1HPGD | |
| SCHEMBL21455821 | 0.71 | L3MBTL1 (0.38) | L3MBTL1RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL25918811 | 0.71 | L3MBTL1 (0.38) | L3MBTL1RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL24200072 | 0.71 | CFD (0.38) | DPP4LMNAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL24200155 | 0.71 | MRGPRX4 (0.35) | L3MBTL1MRGPRX4ALDH1A1CFD | |
| SCHEMBL21455292 | 0.71 | L3MBTL1 (0.37) | DPP4LMNAMAPTL3MBTL1RAB9A | |
| SCHEMBL23617011 | 0.71 | L3MBTL1 (0.35) | LMNAMAPTL3MBTL1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195720-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |