Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455293 | 0.79 | DPP4 (0.35) | L3MBTL1CFDHPGDPARP14PARP10 | |
| SCHEMBL21561862 | 0.79 | TBXAS1 (0.40) | L3MBTL1TBXAS1CFDMEN1KMT2A | |
| SCHEMBL23617011 | 0.78 | L3MBTL1 (0.35) | L3MBTL1TBXAS1MEN1POLBHPGD | |
| SCHEMBL24200072 | 0.77 | CFD (0.38) | L3MBTL1TBXAS1CFDHPGDKDM4E | |
| SCHEMBL24199900 | 0.76 | CFD (0.39) | L3MBTL1TBXAS1CFDPKMALDH1A1 | |
| SCHEMBL21455529 | 0.75 | CFD (0.42) | TBXAS1CFDALDH1A1 | |
| SCHEMBL21455546 | 0.75 | TBXAS1 (0.40) | L3MBTL1TBXAS1MEN1KMT2APKM | |
| SCHEMBL24200109 | 0.74 | TBXAS1 (0.34) | L3MBTL1TBXAS1MEN1KMT2AALDH1A1 | |
| SCHEMBL23241618 | 0.73 | TBXAS1 (0.38) | L3MBTL1TBXAS1MEN1POLBHPGD | |
| SCHEMBL24200164 | 0.73 | CFD (0.42) | TBXAS1CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |