Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29557301 | 1.00 | POLB (0.45) | POLBKDM4ELMNAMAPTMEN1 | |
| SCHEMBL20886449 | 0.91 | POLB (0.47) | POLBKDM4ELMNAMAPTMEN1 | |
| SCHEMBL29556668 | 0.91 | POLB (0.47) | POLBKDM4ELMNAMAPTMEN1 | |
| SCHEMBL15680349 | 0.90 | POLB (0.47) | POLBKDM4ELMNAMAPTMEN1 | |
| SCHEMBL29556671 | 0.90 | POLB (0.47) | POLBKDM4ELMNAMAPTMEN1 | |
| SCHEMBL9356550 | 0.87 | POLB (0.52) | POLBKDM4ELMNAMAPTMEN1 | |
| SCHEMBL12381629 | 0.87 | MAOB (0.50) | POLBKDM4ELMNAMAPTMEN1 | |
| SCHEMBL15680534 | 0.87 | POLB (0.43) | POLBKDM4ELMNAMAPTMEN1 | |
| SCHEMBL15495478 | 0.86 | LMNA (0.47) | POLBKDM4ELMNAMAPTMEN1 | |
| SCHEMBL14699786 | 0.86 | MAPT (0.48) | POLBKDM4ELMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019194306-A1 | NOVEL PENAM DERIVATIVES OR SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | 富士フイルム株式会社 | 2019-10-10 | — | — | WO | disclosed |