Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CDC7 | O00311 | 5/20 | 0.55 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9172563 | 1.00 | TSHR (0.67) | TSHRGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL16099136 | 0.82 | NOTUM (0.42) | TSHRGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL9172544 | 0.82 | NOTUM (0.42) | TSHRGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL3396404 | 0.80 | TSHR (0.78) | TSHRGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL29098331 | 0.79 | HIF1A (0.65) | TSHRGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL8696237 | 0.77 | TSHR (0.72) | TSHRGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL24996925 | 0.76 | NOTUM (0.67) | GAACDC7DBF4 | |
| SCHEMBL30127726 | 0.76 | NOTUM (0.67) | GAACDC7DBF4 | |
| SCHEMBL9254901 | 0.76 | HIF1A (0.61) | TSHRGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL9177182 | 0.73 | RXFP1 (0.40) | TSHRGAAALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976061-B1 | COMBINATIONS OF N-ACETYL CYSTEINE DERIVATIVES AND CRANBERRY POLYPHENOLS IN COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING PERIODONTAL DISEASES AND PERI-IMPLATITIS | DENTALMED PHARM HOLDING LTD (BE) | 2019-10-16 | — | — | EP | claimed |