SCHEMBL21457230

SCHEMBL21457230

COC(=O)C=C(C#N)c1cccc(O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HB P07237 2/20 0.43
KDM4E B2RXH2 5/20 0.42
EGLN2 Q96KS0 1/20 0.42
RAB9A P51151 5/20 0.42
MAPK1 P28482 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA6 P23280 1/20 0.42
CA9 Q16790 1/20 0.42
NPC1 O15118 3/20 0.42
POLB P06746 1/20 0.42
ALDH1A1 P00352 2/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
MAPT P10636 4/20 0.41
MEN1 O00255 2/20 0.41
NFKB1 P19838 2/20 0.41
NFKB2 Q00653 2/20 0.41
KMT2A Q03164 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457324 0.85 AKR1C3 (0.41) KDM4ERAB9ACA12CA1CA2
SCHEMBL21457321 0.85 CES2 (0.54) P4HBKDM4ERAB9AMAPK1NPC1
SCHEMBL21457347 0.85 HDAC8 (0.45) KDM4ERAB9ANPC1POLBALDH1A1
SCHEMBL21457251 0.85 RAB9A (0.45) P4HBKDM4ERAB9AMAPK1CA12
SCHEMBL21457690 0.85 MAPK1 (0.40) P4HBKDM4EEGLN2RAB9AMAPK1
SCHEMBL21457646 0.84 GSK3B (0.50) P4HBGAA
SCHEMBL21457444 0.84 NPC1 (0.49) KDM4ERAB9ANPC1POLBALDH1A1
SCHEMBL21457279 0.84 ALDH1A1 (0.48) KDM4ERAB9ANPC1POLBALDH1A1
SCHEMBL21457567 0.84 SMN1; SMN2 (0.46) KDM4ERAB9AMAPK1NPC1POLB
SCHEMBL23464797 0.83 SMN1; SMN2 (0.50) KDM4ERAB9AMAPK1NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed