SCHEMBL21457765

SCHEMBL21457765

N#C/C(=C\c1ccccc1)C(=O)OC=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.60
ALDH1A1 P00352 5/20 0.52
EGFR P00533 1/20 0.51
KDM4E B2RXH2 3/20 0.50
PLIN1 O60240 1/20 0.50
LMNA P02545 1/20 0.50
PLIN5 Q00G26 1/20 0.50
ABHD5 Q8WTS1 1/20 0.50
POLB P06746 1/20 0.49
PKM P14618 1/20 0.48
KMT2A Q03164 1/20 0.48
ATM Q13315 1/20 0.48
CISD1 Q9NZ45 1/20 0.47
SLC16A3 O15427 1/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.47
SLC16A1 P53985 1/20 0.47
GPR35 Q9HC97 1/20 0.47
MAPT P10636 1/20 0.46
RECQL P46063 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8665795 0.85 MCL1 (0.58) MCL1ALDH1A1EGFRKDM4EPLIN1
SCHEMBL8105743 0.85 MCL1 (0.58) MCL1ALDH1A1EGFRKDM4EPLIN1
SCHEMBL4246049 0.81 MCL1 (0.62) MCL1ALDH1A1KDM4EPLIN1LMNA
SCHEMBL4246045 0.81 MCL1 (0.62) MCL1ALDH1A1KDM4EPLIN1LMNA
SCHEMBL6927070 0.81 MCL1 (0.62) MCL1ALDH1A1KDM4EPLIN1LMNA
SCHEMBL15537245 0.81 MCL1 (0.67) MCL1ALDH1A1EGFRKDM4EPLIN1
SCHEMBL2201000 0.80 MCL1 (0.60) MCL1ALDH1A1EGFRKDM4EPLIN1
SCHEMBL30289962 0.80 ALDH1A1 (0.59) MCL1ALDH1A1EGFRKDM4EPLIN1
SCHEMBL3009380 0.78 KDM4E (0.72) MCL1ALDH1A1EGFRKDM4EPLIN1
SCHEMBL305982 0.78 KDM4E (0.72) MCL1ALDH1A1EGFRKDM4EPLIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed