Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | FABP1 | P07148 | 1/20 | 0.46 |
| ▸ | FABP6 | P51161 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448193 | 0.80 | CYP2D6 (0.59) | CYP2D6FDPSPCSK9CXCR4CYP2C19 | |
| SCHEMBL14198659 | 0.77 | CYP2D6 (0.56) | CYP2D6FDPSPCSK9CXCR4CYP2C19 | |
| SCHEMBL5845328 | 0.77 | CYP2D6 (0.65) | CYP2D6FDPSPCSK9CXCR4CYP2C19 | |
| SCHEMBL6800071 | 0.77 | CYP2D6 (0.65) | CYP2D6FDPSPCSK9CXCR4CYP2C19 | |
| SCHEMBL1831588 | 0.77 | CYP2D6 (0.56) | CYP2D6FDPSPCSK9CXCR4CYP2C19 | |
| SCHEMBL19935946 | 0.77 | CYP2D6 (0.56) | CYP2D6FDPSPCSK9CXCR4CYP2C19 | |
| SCHEMBL9641222 | 0.77 | CXCR4 (0.55) | CYP2D6FDPSCXCR4CYP2C19FABP1 | |
| SCHEMBL25387117 | 0.76 | PCSK9 (0.58) | CYP2D6FDPSPCSK9CXCR4CYP2C19 | |
| SCHEMBL9645509 | 0.76 | CYP2D6 (0.54) | CYP2D6FDPSPCSK9CXCR4CYP2C19 | |
| Bromide SCHEMBL7424239 | 0.75 | CXCR4 (0.53) | CYP2D6FDPSCXCR4CYP2C19FABP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200062710-A1 | Method For Producing 3-(Pyridyl-2-Amino)Propionitrile And Analogues Thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2020-02-27 | — | — | US | disclosed |
| EP-3553051-A1 | METHOD FOR PRODUCING 3-(PYRIDYL-2-AMINO)PROPIONITRILE AND ANALOGUES THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2019-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062710-A1 | Method For Producing 3-(Pyridyl-2-Amino)Propionitrile And Analogues Thereof | PDXK, PAH, PNPO | CYP2D6 87/4885FDPS 143/4885PCSK9 3131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.