SCHEMBL21458073

SCHEMBL21458073

CCNC(=O)C(=O)C(CCc1ccccc1)NC(=O)C(CC(C)C)NC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.50
MMP3 P08254 5/20 0.49
MMP2 P08253 5/20 0.48
MMP8 P22894 1/20 0.48
CTSL P07711 1/20 0.47
MMP1 P03956 1/20 0.47
MMP12 P39900 1/20 0.47
MMP13 P45452 1/20 0.47
MME P08473 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3837984 1.00 ANPEP (0.50) ANPEPMMP3MMP2MMP8CTSL
SCHEMBL3840255 0.88 CAPN1 (0.58) MMP2MMP12MMP13MME
SCHEMBL20474454 0.88 CAPN1 (0.58) MMP2MMP12MMP13MME
SCHEMBL20474455 0.88 CAPN1 (0.58) MMP2MMP12MMP13MME
SCHEMBL21457982 0.87 CAPN1 (0.62) CTSL
SCHEMBL4390231 0.87 CAPN1 (0.62) CTSL
SCHEMBL15304656 0.84 CAPN1 (0.53) ANPEPMMP3MMP2CTSLMMP1
SCHEMBL21457995 0.84 CAPN1 (0.64) ANPEPMMP3MMP2MMP8CTSL
SCHEMBL3844110 0.84 CAPN1 (0.64) ANPEPMMP3MMP2MMP8CTSL
SCHEMBL21458071 0.83 MMP1 (0.44) ANPEPMMP3MMP2MMP8MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11844776-B2 Composition for treatment and/or prevention of peripheral nerve disorder OSAKA CITY UNIVERSITY (JP) 2023-12-19 US disclosed
US-20190314320-A1 COMPOSITION FOR TREATMENT AND/OR PREVENTION OF PERIPHERAL NERVE DISORDER OSAKA CITY UNIVERSITY (JP) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190314320-A1 COMPOSITION FOR TREATMENT AND/OR PREVENTION OF PERIPHERAL NERVE DISORDER PMP22, PRPH, NGF ANPEP 4220/4885MMP3 3124/4885MMP2 2186/4885
US-11844776-B2 Composition for treatment and/or prevention of peripheral nerve disorder PMP22, PRPH, NGF ANPEP 4220/4885MMP3 3124/4885MMP2 2186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.