SCHEMBL21458071

SCHEMBL21458071

CCNC(=O)C(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](CC(C)C)OC(N)=O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.44
MMP2 P08253 1/20 0.44
MMP12 P39900 1/20 0.44
MMP13 P45452 1/20 0.44
MMP8 P22894 4/20 0.43
ERAP2 Q6P179 4/20 0.43
ERAP1 Q9NZ08 4/20 0.43
LNPEP Q9UIQ6 4/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CTSK P43235 1/20 0.42
IL1RN P18510 1/20 0.42
ANPEP P15144 1/20 0.42
LTA4H P09960 1/20 0.42
MMP3 P08254 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457977 0.91 CAPN1 (0.50) MMP1MMP2MMP12MMP13LTA4H
SCHEMBL21458073 0.83 ANPEP (0.50) MMP1MMP2MMP12MMP13MMP8
SCHEMBL3837984 0.83 ANPEP (0.50) MMP1MMP2MMP12MMP13MMP8
SCHEMBL21457982 0.79 CAPN1 (0.62) CTSK
SCHEMBL4390231 0.79 CAPN1 (0.62) CTSK
SCHEMBL5707491 0.77 PSMB1 (0.47) ANPEPLTA4H
SCHEMBL15304656 0.77 CAPN1 (0.53) MMP1MMP2ANPEPMMP3
SCHEMBL21457988 0.76 CAPN1 (0.64) MMP1LTA4H
SCHEMBL20880296 0.74 CAPN1 (0.54) SMN1; SMN2CTSK
SCHEMBL13934277 0.73 CAPN1 (0.47) CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11844776-B2 Composition for treatment and/or prevention of peripheral nerve disorder OSAKA CITY UNIVERSITY (JP) 2023-12-19 US disclosed
US-20190314320-A1 COMPOSITION FOR TREATMENT AND/OR PREVENTION OF PERIPHERAL NERVE DISORDER OSAKA CITY UNIVERSITY (JP) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190314320-A1 COMPOSITION FOR TREATMENT AND/OR PREVENTION OF PERIPHERAL NERVE DISORDER PMP22, PRPH, NGF MMP1 1253/4885MMP2 2186/4885MMP12 4622/4885
US-11844776-B2 Composition for treatment and/or prevention of peripheral nerve disorder PMP22, PRPH, NGF MMP1 1253/4885MMP2 2186/4885MMP12 4622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.