SCHEMBL21461069

SCHEMBL21461069

CC[Si](C)(CC)n1ccnc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.39
QPCT Q16769 1/20 0.39
HSD17B10 Q99714 1/20 0.39
QPCTL Q9NXS2 1/20 0.39
TBXAS1 P24557 2/20 0.36
CYP11B1 P15538 3/20 0.32
CYP11B2 P19099 3/20 0.32
CYP19A1 P11511 2/20 0.31
ALDH1A1 P00352 2/20 0.30
TP53 P04637 1/20 0.30
KDM4E B2RXH2 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL918580 0.81 NFKB1 (0.39) NFKB1QPCTHSD17B10QPCTLTBXAS1
SCHEMBL1953406 0.78 NFKB1 (0.40) NFKB1QPCTHSD17B10QPCTLTBXAS1
SCHEMBL217284 0.74
SCHEMBL10503985 0.74 NFKB1 (0.46) NFKB1QPCTHSD17B10QPCTLTBXAS1
SCHEMBL23302474 0.73 TBXAS1 (0.38) NFKB1QPCTHSD17B10QPCTLTBXAS1
SCHEMBL918938 0.73 TBXAS1 (0.38) NFKB1QPCTHSD17B10QPCTLTBXAS1
Bromide SCHEMBL28508208 0.72 NFKB1 (0.43) NFKB1QPCTHSD17B10QPCTLTBXAS1
SCHEMBL23302390 0.70 TBXAS1 (0.44) NFKB1QPCTHSD17B10QPCTLTBXAS1
SCHEMBL24494655 0.70 NFKB1 (0.33) NFKB1QPCTHSD17B10QPCTLTBXAS1
SCHEMBL1551504 0.70 TBXAS1 (0.44) NFKB1QPCTHSD17B10QPCTLTBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476525-B Method for preparing silica preform for use in the production of optical fibers 普睿司曼股份公司 2021-11-16 CN claimed
US-20190315649-A1 METHOD FOR MANUFACTURING SILICON DIOXIDE PREFORMS EMPLOYED IN THE PRODUCTION OF OPTICAL FIBERS PRYSMIAN S.P.A. (IT) 2019-10-17 US claimed
CN-109476525-A The preparation method for the silica preform applied in production optical fiber 普睿司曼股份公司 2019-03-15 CN claimed
CN-109476525-B Method for preparing silica preform for use in the production of optical fibers 普睿司曼股份公司 2021-11-16 CN disclosed
US-11124442-B2 Method for manufacturing silicon dioxide preforms employed in the production of optical fibers PRYSMIAN S.P.A. (IT) 2021-09-21 US disclosed
US-20190315649-A1 METHOD FOR MANUFACTURING SILICON DIOXIDE PREFORMS EMPLOYED IN THE PRODUCTION OF OPTICAL FIBERS PRYSMIAN S.P.A. (IT) 2019-10-17 US disclosed
CN-109476525-A The preparation method for the silica preform applied in production optical fiber 普睿司曼股份公司 2019-03-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315649-A1 METHOD FOR MANUFACTURING SILICON DIOXIDE PREFORMS EMPLOYED IN THE PRODUCTION OF OPTICAL FIBERS NOXO1, NOX5, NOX4 NFKB1 952/4885QPCT 3716/4885HSD17B10 3627/4885
US-11124442-B2 Method for manufacturing silicon dioxide preforms employed in the production of optical fibers NOXO1, NOX5, NOX4 NFKB1 952/4885QPCT 3716/4885HSD17B10 3627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.