SCHEMBL21462437

SCHEMBL21462437

CCOC(=O)c1c(Cl)c2cc(Cl)cnc2n(C)c1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 3/20 0.43
KDM4E B2RXH2 2/20 0.43
HPGD P15428 2/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
CASP1 P29466 1/20 0.43
MAPT P10636 2/20 0.42
POLB P06746 2/20 0.42
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
MAPK10 P53779 1/20 0.40
HTT P42858 1/20 0.40
CSF1R P07333 1/20 0.39
LMNA P02545 2/20 0.39
PABPC1 P11940 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
FGFR1 P11362 1/20 0.38
KDM5B Q9UGL1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23248374 0.92 ALDH1A1 (0.42) L3MBTL1ALDH1A1HSD17B10KDM4EHPGD
SCHEMBL9261071 0.89 ALDH1A1 (0.54) ALDH1A1HSD17B10KDM4EHPGDALOX15
SCHEMBL20568530 0.88 ALDH1A1 (0.43) L3MBTL1ALDH1A1HSD17B10KDM4ETSHR
SCHEMBL31434014 0.84 MAPT (0.62) L3MBTL1ALDH1A1KDM4EMAPTPOLB
SCHEMBL23248450 0.81 ALDH1A1 (0.51) ALDH1A1HSD17B10KDM4EHPGDALOX15
SCHEMBL11076507 0.81 L3MBTL1 (0.53) L3MBTL1ALDH1A1KDM4EALOX15TSHR
SCHEMBL4847106 0.79 ALDH1A1 (0.48) L3MBTL1ALDH1A1HSD17B10KDM4EHPGD
SCHEMBL11075024 0.78 L3MBTL1 (0.49) L3MBTL1ALDH1A1KDM4EHPGDTSHR
SCHEMBL11313274 0.78 ALDH1A1 (0.60) L3MBTL1ALDH1A1HSD17B10KDM4EHPGD
SCHEMBL9284157 0.77 ALDH1A1 (0.56) L3MBTL1ALDH1A1HSD17B10KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4729127-A2 BCL6 INHIBITORS Cancer Research Technology Limited (GB) 2026-04-22 EP disclosed
US-20260042776-A1 BCL6 INHIBITORS CANCER RESEARCH TECH LTD (GB) 2026-02-12 US disclosed
US-12486285-B2 BCL6 inhibitors CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2025-12-02 US disclosed
CN-112334475-B BCL6 inhibitors 癌症研究技术有限公司 2024-10-29 CN disclosed
US-20240217987-A1 INHIBITOR COMPOUNDS THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2024-07-04 US disclosed
US-20230287003-A1 BCL6 INHIBITORS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2023-09-14 US disclosed
US-20230287003-A1 BCL6 INHIBITORS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2023-09-14 US disclosed
US-20230287003-A1 BCL6 INHIBITORS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2023-09-14 US disclosed
EP-4201939-A1 BCL6 INHIBITORS Cancer Research Technology Limited (GB) 2023-06-28 EP disclosed
EP-3774817-B1 BCL6 INHIBITORS CANCER RESEARCH TECH LTD (GB) 2022-12-07 EP disclosed
EP-3774817-B1 BCL6 INHIBITORS CANCER RESEARCH TECH LTD (GB) 2022-12-07 EP disclosed
US-11512095-B2 BCL6 inhibitors THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2022-11-29 US disclosed
US-20210163497-A1 BCL6 INHIBITORS THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2021-06-03 US disclosed
US-20210163497-A1 BCL6 INHIBITORS THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2021-06-03 US disclosed
EP-3774817-A1 BCL6 INHIBITORS Cancer Research Technology Limited (GB) 2021-02-17 EP disclosed
CN-112334475-A BCL6 inhibitor 癌症研究技术有限公司 2021-02-05 CN disclosed
WO-2019197842-A1 BCL6 INHIBITORS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2019-10-17 WO disclosed
WO-2019197842-A1 BCL6 INHIBITORS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2019-10-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163497-A1 BCL6 INHIBITORS BCL6, BCL6B, BCL3 L3MBTL1 536/4885ALDH1A1 2602/4885HSD17B10 1125/4885
US-20230287003-A1 BCL6 INHIBITORS BCL6, BCL6B, BCL3 L3MBTL1 536/4885ALDH1A1 2602/4885HSD17B10 1125/4885
US-12486285-B2 BCL6 inhibitors BCL6, BCL6B, BCL3 L3MBTL1 536/4885ALDH1A1 2602/4885HSD17B10 1125/4885
US-11512095-B2 BCL6 inhibitors BCL6, BCL6B, BCL3 L3MBTL1 536/4885ALDH1A1 2602/4885HSD17B10 1125/4885
US-20240217987-A1 INHIBITOR COMPOUNDS BCL6, BCL6B, BCL3 L3MBTL1 653/4885ALDH1A1 2960/4885HSD17B10 1571/4885
US-20260042776-A1 BCL6 INHIBITORS BCL6, BCL6B, BCL9 L3MBTL1 1893/4885ALDH1A1 3510/4885HSD17B10 4105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.