Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PCNA | P12004 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CHRND | Q07001 | 5/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.43 |
| ▸ | CHRNG | P07510 | 1/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31072235 | 1.00 | ALDH1A1 (0.48) | ALDH1A1PCNANPSR1BACE1MDM4 | |
| SCHEMBL24091032 | 0.97 | ALDH1A1 (0.46) | ALDH1A1PCNANPSR1BACE1MDM4 | |
| SCHEMBL24091040 | 0.95 | PCNA (0.54) | ALDH1A1PCNANPSR1BACE1MDM4 | |
| SCHEMBL13938296 | 0.91 | ALDH1A1 (0.46) | ALDH1A1PCNANPSR1BACE1MDM4 | |
| SCHEMBL21884113 | 0.91 | ALDH1A1 (0.46) | ALDH1A1PCNANPSR1BACE1MDM4 | |
| SCHEMBL29352083 | 0.90 | ALDH1A1 (0.50) | ALDH1A1NPSR1BACE1MDM4MDM2 | |
| SCHEMBL21466071 | 0.90 | ALDH1A1 (0.50) | ALDH1A1NPSR1BACE1MDM4MDM2 | |
| SCHEMBL4403610 | 0.90 | BACE1 (0.43) | ALDH1A1PCNANPSR1BACE1MDM4 | |
| SCHEMBL16021248 | 0.90 | FOLH1 (0.47) | ALDH1A1PCNAPOLB | |
| Bicarbonate SCHEMBL30452528 | 0.88 | MDM4 (0.51) | ALDH1A1NPSR1BACE1MDM4MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210380761-A1 | CROSS-LINKED RADIOPAQUE BIORESORBABLE POLYMERS AND DEVICES MADE THEREFROM | REVA MEDICAL, LLC | 2021-12-09 | — | — | US | disclosed |
| WO-2020033521-A1 | CROSS-LINKED RADIOPAQUE BIORESORBABLE POLYMERS AND DEVICES MADE THEREFROM | REVA MEDICAL, INC. (US) | 2020-02-13 | — | — | WO | disclosed |
| US-20100262182-A1 | Occlusion Instruments Comprising Bioresorbable Radiopaque Polymeric Materials, As Well As Related Products, Methods And Uses | OCCLUTECH GMBH | 2010-10-14 | — | — | US | disclosed |
| US-20100262182-A1 | Occlusion Instruments Comprising Bioresorbable Radiopaque Polymeric Materials, As Well As Related Products, Methods And Uses | OCCLUTECH GMBH | 2010-10-14 | — | — | US | disclosed |