Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 6/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18022788 | 0.82 | LMNA (0.38) | KDM4ELMNAALDH1A1SLC22A2SLC22A1 | |
| SCHEMBL18022784 | 0.81 | KDM4E (0.50) | KDM4ETSHRBLMPMP22BRD4 | |
| SCHEMBL16560322 | 0.77 | MAOB (0.51) | KDM4ETSHRBLMPMP22NPC1 | |
| SCHEMBL16631768 | 0.75 | EPHX2 (0.44) | LMNAALDH1A1MAPK1 | |
| SCHEMBL2232095 | 0.74 | LMNA (0.57) | KDM4ELMNAALDH1A1SLC22A2SLC22A1 | |
| SCHEMBL6726005 | 0.74 | BRD4 (0.47) | LMNANPC1RAB9ABRD4MAPK8 | |
| SCHEMBL13043368 | 0.74 | KDM4E (0.51) | KDM4ELMNAALDH1A1TSHRNPC1 | |
| SCHEMBL13043703 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1TSHRNPC1RAB9A | |
| Acetone SCHEMBL28835039 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1NPC1RAB9ACYP19A1 | |
| SCHEMBL14159023 | 0.72 | CYP1A2 (0.63) | ALDH1A1TSHRMAPK1BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10441669-B2 | Multifunctional chelators, complexes, and compositions thereof, and methods of using same | ILLINOIS INSTITUTE OF TECHNOLOGY (US) | 2019-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10441669-B2 | Multifunctional chelators, complexes, and compositions thereof, and methods of using same | FECH, SLC40A1, TFRC | KDM4E 3507/4885LMNA 1334/4885ALDH1A1 4350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.