Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 15/20 | 0.52 |
| ▸ | NPC1 | O15118 | 12/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 8/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 8/20 | 0.52 |
| ▸ | RELA | Q04206 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21499351 | 0.85 | PDE7A (0.47) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL21468460 | 0.79 | DHODH (0.59) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21499310 | 0.76 | RXRA (0.37) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18407360 | 0.76 | PTPN1 (0.56) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21468516 | 0.74 | NPC1 (0.68) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL17936101 | 0.74 | BTK (0.41) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21468501 | 0.72 | DHODH (0.39) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL28255492 | 0.71 | NPC1 (0.71) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL21133751 | 0.69 | POLB (0.46) | RAB9ANPC1POLBMAPTHTT | |
| SCHEMBL2244056 | 0.69 | BAZ2B (0.67) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450263-B2 | Benzo annulenes as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2019-10-22 | — | — | US | disclosed |
| US-10450263-B2 | Benzo annulenes as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450263-B2 | Benzo annulenes as antiviral agents | MAVS, ZC3HAV1, GABBR1 | RAB9A 1314/4885NPC1 908/4885SMN1; SMN2 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.