Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21468476 | 0.76 | RAB9A (0.52) | ALDH1A1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL21468484 | 0.73 | NR1H4 (0.55) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL24415622 | 0.71 | HDAC3 (0.36) | HSD17B1HSD17B2BTKALDH1A1NPC1 | |
| SCHEMBL21468460 | 0.67 | DHODH (0.59) | ALDH1A1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL11667482 | 0.66 | RXRA (0.58) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL21468523 | 0.64 | DHODH (0.47) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL16814173 | 0.63 | ALDH1A1 (0.44) | BTKALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL4282035 | 0.63 | HCAR2 (0.57) | RXRARXRBRXRGBTKALDH1A1 | |
| SCHEMBL2091407 | 0.62 | RXRA (0.48) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL27666257 | 0.62 | RXRA (0.48) | RXRARXRBRXRGALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450263-B2 | Benzo annulenes as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450263-B2 | Benzo annulenes as antiviral agents | MAVS, ZC3HAV1, GABBR1 | RXRA 2532/4885RXRB 2362/4885RXRG 3246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.