Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GCK | P35557 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CCND3 | P30281 | 1/20 | 0.30 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25162079 | 0.84 | P2RX3 (0.33) | P2RX3MEN1KMT2AKDM4C | |
| SCHEMBL24075269 | 0.80 | — | — | |
| SCHEMBL25162393 | 0.75 | — | — | |
| SCHEMBL21468904 | 0.74 | MEN1 (0.32) | MEN1KMT2AKDM4C | |
| SCHEMBL21468906 | 0.73 | DHODH (0.41) | — | |
| SCHEMBL25515657 | 0.72 | CDK4 (0.33) | P2RX3MEN1KMT2ACDK4CCND1 | |
| SCHEMBL24075279 | 0.72 | DHODH (0.37) | — | |
| SCHEMBL25162459 | 0.71 | DHODH (0.41) | — | |
| SCHEMBL29251241 | 0.71 | DHODH (0.49) | — | |
| SCHEMBL3519226 | 0.68 | PDE8B (0.33) | P2RX3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019197239-A1 | METHOD FOR THE PREPARATION OF A 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONE | BAYER AKTIENGESELLSCHAFT (DE) | 2019-10-17 | — | — | WO | disclosed |