Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3522758 | 0.84 | MEN1 (0.35) | P2RX3MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL21468904 | 0.82 | MEN1 (0.32) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL21469054 | 0.72 | P2RX3 (0.35) | CDK4CCND1CCND3CDK6P2RX3 | |
| SCHEMBL25162079 | 0.68 | P2RX3 (0.33) | P2RX3MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL15742170 | 0.67 | CDK4 (0.40) | CDK4CCND1CCND3CDK6MEN1 | |
| SCHEMBL30888969 | 0.66 | CDK4 (0.49) | CDK4CCND1CCND3CDK6P2RX3 | |
| SCHEMBL12126157 | 0.65 | KDM4C (0.41) | P2RX3MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL7243739 | 0.63 | KDM4C (0.39) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL4496192 | 0.62 | MEN1 (0.36) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL15728474 | 0.62 | KDM4C (0.38) | MEN1KMT2AKDM4CNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093812-A1 | CRYSTAL FORM OF TRIAZOLONE COMPOUND AND USE THEREOF | 南京明德新药研发有限公司 | 2023-06-01 | — | — | WO | disclosed |