SCHEMBL21469151

SCHEMBL21469151

Cc1ccc(N=Nc2cccc3ccccc23)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.68
KMT2A Q03164 8/20 0.68
L3MBTL1 Q9Y468 7/20 0.68
NPC1 O15118 6/20 0.68
RAB9A P51151 5/20 0.68
MAPT P10636 6/20 0.48
TDP1 Q9NUW8 6/20 0.48
ALDH1A1 P00352 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
LMNA P02545 3/20 0.48
HTT P42858 1/20 0.48
KCNH2 Q12809 1/20 0.48
POLB P06746 1/20 0.45
APOBEC3A P31941 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
MAPK1 P28482 4/20 0.44
PKM P14618 1/20 0.44
ATM Q13315 1/20 0.44
SCN2A Q99250 1/20 0.44
CCNE2 O96020 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14603034 1.00 MEN1 (0.68) MEN1KMT2AL3MBTL1NPC1RAB9A
SCHEMBL23257776 0.86 MEN1 (0.53) MEN1KMT2AL3MBTL1NPC1RAB9A
SCHEMBL10602984 0.86 MEN1 (0.53) MEN1KMT2AL3MBTL1NPC1RAB9A
SCHEMBL11004070 0.86 MEN1 (0.53) MEN1KMT2AL3MBTL1NPC1RAB9A
SCHEMBL6123887 0.85 MEN1 (0.50) MEN1KMT2AL3MBTL1NPC1RAB9A
SCHEMBL2926925 0.84 MEN1 (0.55) MEN1KMT2AL3MBTL1NPC1RAB9A
Azobenzene SCHEMBL11130609 0.84 MEN1 (0.55) MEN1KMT2AL3MBTL1NPC1RAB9A
SCHEMBL2926928 0.84 MEN1 (0.55) MEN1KMT2AL3MBTL1NPC1RAB9A
Azobenzene SCHEMBL11226032 0.84 MEN1 (0.55) MEN1KMT2AL3MBTL1NPC1RAB9A
SCHEMBL28219746 0.84 MEN1 (0.49) MEN1KMT2AL3MBTL1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11384381-B2 Reaction accelerating agent KIKKOMAN CORPORATION (JP) 2022-07-12 US disclosed
US-20190316174-A1 REACTION ACCELERATING AGENT KIKKOMAN CORPORATION (JP) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11384381-B2 Reaction accelerating agent MPO, AOX1, MAOA MEN1 3767/4885KMT2A 1992/4885L3MBTL1 4849/4885
US-20190316174-A1 REACTION ACCELERATING AGENT MPO, AOX1, MAOA MEN1 3767/4885KMT2A 1992/4885L3MBTL1 4849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.